72726-49-9

Basic information

• Product Name: Silane, (2-cyclohexen-1-yloxy)(1,1-dimethylethyl)dimethyl-
• CAS NO: 72726-49-9
• Molecular Formula: C12H24OSi
• Molecular Weight: 212.407
• Mol File: 72726-49-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Silane, (2-cyclohexen-1-yloxy)(1,1-dimethylethyl)dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (2-cyclohexen-1-yloxy)(1,1-dimethylethyl)dimethyl-(72726-49-9)
• EPA Substance Registry System: Silane, (2-cyclohexen-1-yloxy)(1,1-dimethylethyl)dimethyl-(72726-49-9)

Safety Data

• Hazardous Substances Data: 72726-49-9(Hazardous Substances Data)

Upstream product

• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 
• 822-67-3 Cyclohex-2-enol 
• 72726-46-6 tert-butyl(dimethyl)(phenylseleno)silane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 286-20-4 cyclohexane-1,2-epoxide 
• 72726-45-5 tert-butyldimethylsilyl iodide 

Downstream Products

• 73795-22-9 3-t-butyldimethylsiloxy-2-phenylselenocyclohexanone 
• 102922-54-3 (1β,2α)-2-(oxy)-1-cyclohexanol 
• 102922-54-3 cis-2-(tert-butyldimethylsilyloxy)-1-cyclohexanol 
• 116565-14-1 (1R^*,3R^*)-3-<(tert-butyldimethylsilyl)oxy>cyclohexanol 
• 116565-14-1 (1S^*,3R^*)-3-<(tert-butyldimethylsilyl)oxy>cyclohexanol 
• 70810-37-6 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene 
• 579488-71-4 methyl 3-(2-(tert-butyldimethylsilyloxy)cyclohexyl)-2-(2-pyridylsulfanyl)propanoate 
• 579488-74-7 methyl 3-(3-(tert-butyldimethylsilyloxy)cyclohexyl)-2-(2-pyridylsulfanyl)propanoate 
• 80684-13-5 3-t-butyldimethylsiloxycyclohexanone 
• 125488-60-0 tert-Butyl-(3-isocyano-cyclohex-2-enyloxy)-dimethyl-silane 
• 125488-55-3 tert-Butyl-((2R,3S)-2-iodo-3-isocyano-cyclohexyloxy)-dimethyl-silane 
• 1384870-20-5 C₁₅H₂₀N₂O₃S 

Relevant articles and documents

PYRAZOLOPYRIMIDINE INHIBITORS OF IRAK4 ACTIVITY

The present invention relates to pyrazolopyrimidine inhibitors of IRAK4 of formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.

FUSED HETEROAROMATIC PYRROLIDINONES

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, L1, L2, R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.

Syntheses of seven-membered rings: Ruthenium-catalyzed intramolecular [5+2] cycloadditions

The Ru-catalyzed intramolecular [5+2] cycloaddition of cyclopropylenynes is investigated with respect to the regio- and diastereoselectivity as well as the functional group compatibility of the reaction. Evidence for the mechanism as occurring through a ruthenacyclopentene intermediate is elucidated from 1) the study of the diastereoselectivity of the cycloaddition; 2) the effect of variation of substituents on the regioselectivity of cyclopropyl bond cleavage in 1,2-trans- and 1,2-cis-disubstituted cyclopropanes and 3) examples that clearly do not involve ruthenacyclohexene as intermediates as products still incorporate the cyclo propyl moiety. The scope and limitations of the Ru-catalyzed cycloaddition are discussed and compared with the Rh-catalyzed reaction. The potential power of this methodology towards natural product total synthesis is demonstrated by the formation of several polycyclic systems with the chosen reaction conditions and readily available cyclopropylenyne substrates.