727404-86-6Relevant articles and documents
Synthesis of 7-alkoxy/hydroxy-α-methyltryptamines
Dubash, Nauzer P.,Mangu, Naveen K.,Satyam, Apparao
, p. 1791 - 1799 (2004)
A simple method for the preparation of 7-alkoxy/hydroxy-α -methyl-DL-tryptamines is reported. The key steps of the synthesis are the Japp-Klingemann coupling of 2-piperidone-3-carboxylic acid 3 with diazonium salts 4, the Fischer-type cyclization of hydrazones 5 to β-carboline derivatives 6 and their hydrolysis to title compounds 8.