72790-89-7 Usage
General Description
1-Methylcyclopropanecarbohydrazide is a chemical compound in the category of organic compounds known as hydrazides. Its chemical structure consists of a cyclopropane ring bonded with a methyl group and a carbohydrazide moiety. It is characterized by the presence of a hydrazide group (-CONHNH2), which is an organic functional group derived from carboxylic acids and hydrazine. This chemical compound is not extensively studied or widely used, hence details regarding its physical and chemical properties, potential uses, or health implications are not readily available or scientifically established.
Check Digit Verification of cas no
The CAS Registry Mumber 72790-89-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,7,9 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 72790-89:
(7*7)+(6*2)+(5*7)+(4*9)+(3*0)+(2*8)+(1*9)=157
157 % 10 = 7
So 72790-89-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O/c1-5(2-3-5)4(8)7-6/h2-3,6H2,1H3,(H,7,8)
72790-89-7Relevant articles and documents
Development of orally active nonpeptidic inhibitors of human neutrophil elastase
Ohmoto,Yamamoto,Okuma,Horiuchi,Imanishi,Odagaki,Kawabata,Sekioka,Hirota,Matsuoka,Nakai,Toda,Cheronis,Spruce,Gyorkos,Wieczorek
, p. 1268 - 1285 (2007/10/03)
5-Amino-2-phenylpyrimidin-6-ones, some of their desamino derivatives, and miscellaneous derivatives were synthesized and biologically evaluated on both in vitro activity and oral activity in an acute hemorrhagic assay. These compounds contained an α-keto-1,3,4-oxadiazole moiety to bind covalently to the Ser-195 hydroxy group of human neutrophil elastase (HNE). Among those tested, compounds 11a-c,e,i-l(F), 11d,e,k(H), 21d,e,k(F), and 21d,e(H) showed a good oral profile. RS-Mixture 3(H) was selected for clinical evaluation based on its oral potency, duration of action, enzyme selectivity, safety profile, and ease of synthesis. Structure -activity relationships (SARs) are discussed.