727991-07-3Relevant articles and documents
An investigation of construction of chondroitin sulfate E (CS-E) repeating unit
Yang, Shuang,Wang, A-peng,Zhang, Guangyan,Di, Xiangjie,Zhao, Zhehui,Lei, Pingsheng
, p. 5659 - 5670 (2016/08/23)
A series of the derivatives of chondroitin sulfate E (CS-E) disaccharide repeating unit were prepared by postglycosylation–oxidation strategy. The strategy showed excellent performance in glycosylation both on the reactivity and stereoselectivity. Different protecting methodologies were used for the manipulation of disaccharide building blocks. Substitutes at C-4 of glucosyl donors mildly influenced the glycosylation. The current synthesis afforded a feasible approach for the preparation of CS-E repeating unit.
A chondroitin sulfate small molecule that stimulates neuronal growth
Tully, Sarah E.,Mabon, Ross,Gama, Cristal I.,Tsai, Sherry M.,Liu, Xuewei,Hsieh-Wilson, Linda C.
, p. 7736 - 7737 (2007/10/03)
Chondroitin sulfate glycosaminoglycans are sulfated polysaccharides involved in cell division, neuronal development, and spinal cord injury. Here, we report the synthesis and identification of a chondroitin sulfate tetrasaccharide that stimulates the grow