72814-05-2Relevant articles and documents
Synthesis of N,N'-dimethyl diazacoronands via double-quaternization reaction
Jurczak,Ostaszewski,Salanski,Stankiewicz
, p. 1471 - 1477 (2007/10/02)
α,ω-Tertiary diamines react under high pressure with α,ω-di-lodo compounds to give the cyclic bis-quaternary salts in almost quantitative yields. It is also shown that the same reaction can be carried out under atmospheric-pressure conditions with slightly lower yields. Subsequent demethylation of the bis-quaternary salts with triphenylphosphine affords N,N'-dimethyl diazcoronands in high yield.