72853-47-5

Basic information

• Product Name: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester, (2E)-
• Synonyms: (+-)-1-Hydroxy-1-phenyl-penten-(3t)-saeure-(5)-methylester;methyl 5-hydroxy-5-phenyl-2-pentenoate;(E)-Methyl 5-hydroxy-5-phenyl-2-pentenoate;5-hydroxy-5-phenyl-pent-2-enoic acid methyl ester;2-Pentenoic acid,5-hydroxy-5-phenyl-,methyl ester,(2E);(+-)-1-hydroxy-1-phenyl-penten-(3t)-oic acid-(5)-methyl ester
• CAS NO: 72853-47-5
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 72853-47-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 339.8±42.0 °C(Predicted)
• Density: 1.123±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester, (2E)-(72853-47-5)
• EPA Substance Registry System: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester, (2E)-(72853-47-5)

Safety Data

• Hazardous Substances Data: 72853-47-5(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 107-93-7 (E)-but-2-enoic acid 
• 100-52-7 benzaldehyde 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 623-43-8 crotonic acid methyl ester 
• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 292638-85-8 acrylic acid methyl ester 
• 85636-50-6 1-(trimethylsiloxy)-1-methoxy-1,3-butadiene 
• 3724-55-8 methyl but-3-enoate 
• 77-78-1 dimethyl sulfate 
• 3724-65-0 2-butenoic acid 

Downstream Products

• 1004960-84-2 5-hydroxy-5-phenyl-pent-2-enoic acid methyl ester 
• 765940-99-6 (R)-(+)-5,6-dihydro-6-phenylpyran-2-one 
• 112607-33-7 (+)-(R)-δ-(phenyl)-δ-valerolactone 
• 4660-17-7 rac-6-phenyl-5,6-dihydro-2H-pyran-2-one 
• 10413-17-9 6-phenyltetrahydropyran-2-one 
• 37464-83-8 methyl 5-hydroxy-5-phenylpentanoate 
• 112022-82-9 (5R) methyl 5-hydroxy-5-phenylpentanoate 

Relevant articles and documents

One-pot vinylogous aldol addition of β,γ-unsaturated esters under mild conditions

We described a one-pot vinylogous aldol addition of methyl 3-butenoate to aromatic aldehydes in the presence of silver salts and the TMSCl-TBAF mixture. The reaction can be done simply by sequentially mixing reagents in situ, and it does not require any c

Diastereoselective synthesis of trifluoromethylated 1,3-dioxanes by intramolecular oxa-Michael reaction

A highly diastereoselective synthesis of trifluoromethylated 1,3-dioxanes is described. The reaction proceeds by an addition/oxa-Michael sequence and works efficiently under mild reaction conditions, with a good substrate scope and acceptable to good yiel

Enantioselective syntheses of cryptocarya triacetate, Cryptocaryolone, and cryptocaryolone diacetate

(Matrix presented) The enantioselective syntheses of three natural products from Cryptocarya latifolia have been achieved in 13-15 steps from ethyl sorbate. The route relies upon an enantio- and regioselective Sharpless dihydroxylation and a palladium-cat