72861-80-4Relevant articles and documents
Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity
Ragab, Mahmoud A.,Elagawany, Mohamed,Daabees, Hoda,Ahmed, Al-Shaimaa F.,Awad, Eman M.,Billon, Cyrielle,Elgendy, Bahaa,Abouzid, Khaled A.M.,Kassab, Shaymaa E.
, (2021/12/20)
Nuclear Estrogen receptors (ER) are cytoplasmic proteins; translocated to the nucleus to induce transcriptional signals after getting bound to the estrogen hormone. ER activation implicated in cancer cell proliferation of female reproductive organs. Thus,
Claisen-Schmidt, aza-Michael, cyclization via cascade strategy toward microwave promoted synthesis of imidazo[2,1-b]quinazolines
Devi Priya, Duraipandi,Mohana Roopan, Selvaraj
, p. 1813 - 1834 (2020/05/25)
Imidazole blended quinazolines are having a wide run of potential applications in synthetic field. In this current investigation, we reported a modern synthesis with the help of non-conventional energy. Optimization parameters have been stabilized utilizi
Studies in Antifertility Agents: Part XXVIII-1,2-trans-1-(p-(&β-Pyrrolidinoethoxy)phenyl)-2-substituted-benzyl-6-methoxy-1,2,3,4-tetrahydronaphthalenes
Tewari, S. C.,Rastogi, Shri Nivas
, p. 1060 - 1064 (2007/10/02)
Substituted 2-benzyl-6-methoxy-1-tetralones (8-10), obtained by catalytic hydrogenation of 2-arylidene-1-tetralones (5-7), on NaBH4 reduction give a mixture of 1,2-trans-/cis-isomers of 2-benzyl-1-tetralols (11-13).Ac2O-pyridine treatment of 11 furnishes
