729-02-2

Basic information

• Product Name: 4`-ethoxybiphenyl-3-carboxylic acid
• Synonyms: 4`-ethoxybiphenyl-3-carboxylic acid
• CAS NO: 729-02-2
• Molecular Weight: 242.274
• Mol File: 729-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4`-ethoxybiphenyl-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4`-ethoxybiphenyl-3-carboxylic acid(729-02-2)
• EPA Substance Registry System: 4`-ethoxybiphenyl-3-carboxylic acid(729-02-2)

Safety Data

• Hazardous Substances Data: 729-02-2(Hazardous Substances Data)

Upstream product

• 585-76-2 m-bromobenzoic acid 
• 22237-13-4 (4-ethoxyphenyl)boronic acid 

Relevant articles and documents

Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)

High serum fatty acid (FA) levels are causally linked to the development of insulin resistance, which eventually progresses to type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) generalized in the term metabolic syndrome. Adipose triglyceride lipase (ATGL) is the initial enzyme in the hydrolysis of intracellular triacylglycerol (TG) stores, liberating fatty acids that are released from adipocytes into the circulation. Hence, ATGL-specific inhibitors have the potential to lower circulating FA concentrations, and counteract the development of insulin resistance and NAFLD. In this article, we report about structure–activity relationship (SAR) studies of small molecule inhibitors of murine ATGL which led to the development of Atglistatin. Atglistatin is a specific inhibitor of murine ATGL, which has proven useful for the validation of ATGL as a potential drug target.