729590-57-2

Basic information

• Product Name: 4-Benzyloxy-1-broMo-2-chloro-benzene
• Synonyms: 4-Benzyloxy-1-broMo-2-chloro-benzene;1-bromo-2-chloro-4-phenylmethoxybenzene
• CAS NO: 729590-57-2
• Molecular Formula: C₁₃H₁₀BrClO
• Molecular Weight: 297.5749
• Mol File: 729590-57-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 375.8±27.0 °C(Predicted)
• Appearance: /
• Density: 1.471±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Benzyloxy-1-broMo-2-chloro-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Benzyloxy-1-broMo-2-chloro-benzene(729590-57-2)
• EPA Substance Registry System: 4-Benzyloxy-1-broMo-2-chloro-benzene(729590-57-2)

Safety Data

• Hazardous Substances Data: 729590-57-2(Hazardous Substances Data)

Usage

General Description

4-Benzyloxy-1-bromo-2-chloro-benzene is an organic compound with the chemical formula C13H10BrClO. It is a benzene derivative with a bromo and chloro substituent, as well as a benzyloxy group. 4-Benzyloxy-1-broMo-2-chloro-benzene is commonly used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It can also act as a building block for the synthesis of various other chemical compounds. 4-Benzyloxy-1-bromo-2-chloro-benzene is typically handled and stored under controlled conditions due to its potential hazards and reactivity.

Upstream product

• 13631-21-5 4-bromo-3-chlorophenol 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 729590-58-3 C₁₈H₁₇ClO₃ 
• 1437776-42-5 1-(azetidin-1-yl)-2-[2-chloro-4-(2-{(1S,2R)-2-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]cyclopropyl}ethoxy)phenyl]ethanone 
• 1402554-79-3 1-(azetidin-1-yl)-2-(2-chloro-4-hydroxyphenyl)ethanone 
• 1402554-78-2 1-(azetidin-1-yl)-2-[4-(benzyloxy)-2-chlorophenyl]ethanone 
• 70757-43-6 [4-(benzyloxy)-2-chlorophenyl]acetic acid 
• 1402554-77-1 tert-butyl [4-(benzyloxy)-2-chlorophenyl]acetate 
• 1284230-21-2 (R)-3-(benzyloxy)-5-(4-methoxyphenyl)-5,6,6a,7,8,9-hexahydrophenanthridine 
• 1284229-84-0 3-(benzyloxy)-5-(4-methoxyphenyl)-5,6,6a,7,8,9-hexahydrophenanthridine 
• 1438429-23-2 N-[6-[2-chloro-4-(phenylmethoxy)phenyl]-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-indazol-3-yl]butanamide 
• 1131890-62-4 (E)-6-(benzyloxy)-1-phenyl-2-styryl-1H-indole 

Relevant articles and documents

A re-investigation of the Fries rearrangement of 3-chlorophenyl acetate and synthesis of 2-azido-1-(4-(benzyloxy)-2-chlorophenyl)ethanone from 4-bromo-3-chlorophenol

The Fries rearrangement of 3-chlorophenyl acetate provided the expected 4-chloro-2-hydroxy-acetophenone as the major product and 2,4-diacetyl resorcinol and 2-chloro-4-hydroxy-acetophenone as minor products. 4-Benzyloxy-2-chloroacetophenone was prepared by a Heck reaction and then elaborated to 4-benzyloxy-2-chlorophenacyl azide.

SUBSTITUTED CYCLOPROPYL COMPOUNDS USEFUL AS GPR119 AGONISTS

Substituted cyclopropyl compounds of the formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included

CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE

This invention provides cyclicamino-phenyl sulfamate derivatives represented by a formula wherein each of R1 and R2 stands for hydrogen or lower alkyl; each of R3 and R4 stands for hydrogen, halogen, cyano or the like; A stands for nitrogen or CH; B stands for CH2, SO2, CO, optionally substituted phenyl or the like; and R5 stands for alkyl, phenyl, amino or the like, or salts thereof which exhibit excellent steroid sulfatase inhibitory activity and are useful for prevention or treatment of diseases associated with steroids such as estrogen, androgen and the like.