72963-77-0 Usage
Description
1-Deoxyforskolin is a naturally occurring compound derived from the plant Coleus forskohlii. It possesses various biological activities and has been the subject of research for its potential therapeutic applications.
Uses
Used in Pharmaceutical Industry:
1-Deoxyforskolin is used as an active compound for its anti-HIV properties, specifically against the HIVNL4-3 strain. It demonstrates the ability to inhibit the replication of the virus, making it a potential candidate for the development of antiretroviral drugs.
Additionally, 1-Deoxyforskolin is used as an activator of mammalian membranous adenylyl cyclase (AC) isoforms I-VIII. This activation can lead to various physiological effects, such as increased cyclic AMP levels, which may have potential applications in the treatment of certain diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 72963-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,6 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72963-77:
(7*7)+(6*2)+(5*9)+(4*6)+(3*3)+(2*7)+(1*7)=160
160 % 10 = 0
So 72963-77-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H34O6/c1-8-19(5)12-14(24)22(26)20(6)11-9-10-18(3,4)16(20)15(25)17(27-13(2)23)21(22,7)28-19/h8,15-17,25-26H,1,9-12H2,2-7H3/t15-,16-,17-,19-,20-,21+,22-/m0/s1
72963-77-0Relevant articles and documents
ISOLATION, STRUCTURE ELUCIDATION AND SYNTHESIS OF 1-DEOXYFORSKOLIN
Khandelwal, Y.,Jotwani, B. R.,Inamdar, P. K.,Souza, N. J. de,Rupp, R. H.
, p. 763 - 766 (1989)
Isolation and structure elucidation of 1-deoxyforskolin (2), a minor forskolin related constituent, of the Indian herb Coleus forskohlii are described.The structure of 2 is confirmed by the 9-hydroxylation of 1,9-dideoxyforskolin (4).
