73035-26-4

Basic information

• Product Name: ethyl 6-amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylate
• Synonyms: 4H-Pyran-3-carboxylic acid, 6-amino-5-cyano-2,4-diphenyl-, ethyl ester; 6-Amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylic acid ethyl ester; Ethyl 6-amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylate
• CAS NO: 73035-26-4
• Molecular Formula: C₂₁H₁₈N₂O₃
• Molecular Weight: 346.3792
• Mol File: 73035-26-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 588.3°C at 760 mmHg
• Flash Point: 309.6°C
• Density: 1.27g/cm³
• Vapor Pressure: 8.08E-14mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: ethyl 6-amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylate(73035-26-4)
• EPA Substance Registry System: ethyl 6-amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylate(73035-26-4)

Safety Data

• Hazardous Substances Data: 73035-26-4(Hazardous Substances Data)

Upstream product

• 39626-31-8 ethyl 2-benzoyl-3-phenylacrylate 
• 109-77-3 malononitrile 
• 100-52-7 benzaldehyde 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 54797-42-1 2-oxo-2-phenylethyl propionate 

Downstream Products

• 107200-04-4 2-(N-Acetylamino)-5-ethoxycarbonyl-4,6-diphenyl-4H-pyran-3-carbonitrile 
• 709-79-5 (E)-2-cyano-3-phenylacrylamide 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 75617-38-8 3-cyano-5-ethoxycarbonyl-4,6-diphenyl-3,4-dihydropyridin-2(1H)-one 
• 75617-39-9 2-amino-5-carbethoxy-3-cyano-4,6-diphenylpyridine 
• 75617-36-6 ethyl 5-cyano-1,6-dihydro-6-oxo-2,4-diphenyl-3-pyridinecarboxylate 
• 70183-20-9 4-(4-chlorophenyl)-6-oxo-2-phenyl-1,6-dihydro-5-pyrimidinecarbonitrile 

Relevant articles and documents

Synthesis of pyridinium-based salts: Catalytic application at the synthesis of six membered O-heterocycles

In this paper, a range of pyridinium-based ionic liquid (IL) and molten salts (MSs) with various counter ions were designed, synthesized and fully characterized. These novel ionic liquid and molten salts were prepared via the reaction of [PySO3

A Novel Synthesis of Some 1,4-Phenylene-bis-heterocyclic Derivatives and of Some Pyran, Pyrano[2,3-c]pyrazole, and Pyrano[2,3-d]pyrimidine Derivatives [1]

p-Diacetyl benzene 1 undergoes bromination to afford p-bromoacetyl phenacyl bromide 2. Compound 2 reacts with twofold excess of malononitrile to afford 2-{2-[4-(3,3-Dicyanopropionyl)-phenyl]-2-oxo-ethyl}-malononitrile 3. Compound 3 could be cyclized to af

Organocatalysis in synthesis: L-proline as an enantioselective catalyst in the synthesis of pyrans and thiopyrans

The multicomponent reaction (MCR) of aromatic aldehydes 1 and malononitrile (2) with active methylenes 5a-h in the presence of L-proline produced pyrans and thiopyrans 6a-h stereospecifically and in good yields. Moreover a novel MCR of ethyl propiolate (8) with 1 and 2 in the presence of L-proline to afford (R)-polysubstituted pyran is also reported. X-ray structures, e.e. and optical activity of the synthesized compounds indicated that L-proline as a catalyst is responsible for the observed enantioselectivity in the studied reactions.