730926-74-6

Basic information

• Product Name: Hydroxylamine, O-[3-(4-methoxyphenyl)-2-propynyl]- (9CI)
• Synonyms: Hydroxylamine, O-[3-(4-methoxyphenyl)-2-propynyl]- (9CI)
• CAS NO: 730926-74-6
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.19984
• Product Categories: METHOXY
• Mol File: 730926-74-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Hydroxylamine, O-[3-(4-methoxyphenyl)-2-propynyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxylamine, O-[3-(4-methoxyphenyl)-2-propynyl]- (9CI)(730926-74-6)
• EPA Substance Registry System: Hydroxylamine, O-[3-(4-methoxyphenyl)-2-propynyl]- (9CI)(730926-74-6)

Safety Data

• Hazardous Substances Data: 730926-74-6(Hazardous Substances Data)

Upstream product

• 173019-85-7 3-bromo-1-(4-methoxyphenyl)propyne 
• 149929-78-2 N-(3-(4,-Methoxyphenyl)-2-propynyl)-oxyphthalimide 
• 37614-59-8 4-(4-methoxyphenyl)prop-2-yn-1-ol 
• 696-62-8 para-iodoanisole 

Downstream Products

• 1287768-89-1 isopropyl (3-(4-methoxyphenyl)-2-propynyl)oxycarbamate 
• 1287768-71-1 benzyl (3-(4-methoxylphenyl)-2-propynyl)oxycarbamate 
• 1287769-22-5 4-iodo-3-(4-methoxylphenyl)isoxazole 
• 1287769-09-8 benzyl 2,5-dihydro-4-iodo-3-(4-methoxylphenyl)-2H-isoxazole-2-carboxylate 

Relevant articles and documents

Iodocyclization of hydroxylamine derivatives based on the control of oxidative aromatization leading to 2,5-dihydroisoxazoles and isoxazoles

An efficient method for the synthesis of 2,5-dihydroisoxazoles and isoxazoles using iodocyclization of N-alkoxycarbonyl O-propargylic hydroxylamines has been developed. 2,5-Dihydro-4-iodoisoxazole underwent the cross-coupling reactions without aromatization to afford polyfunctionalized 2,5-dihydroisoxazoles. This process was applied to the preparation of valdecoxib and its 2,5-dihydro-derivative.