73183-24-1

Basic information

• Product Name: 2-(4-cyanophenyl)-2-(trimethylsilyloxy)acetonitrile
• Synonyms: 2-(4-cyanophenyl)-2-(trimethylsilyloxy)acetonitrile
• CAS NO: 73183-24-1
• Molecular Weight: 230.341
• Mol File: 73183-24-1.mol
• Article Data: 38

Chemical Properties

• CAS DataBase Reference: 2-(4-cyanophenyl)-2-(trimethylsilyloxy)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-cyanophenyl)-2-(trimethylsilyloxy)acetonitrile(73183-24-1)
• EPA Substance Registry System: 2-(4-cyanophenyl)-2-(trimethylsilyloxy)acetonitrile(73183-24-1)

Safety Data

• Hazardous Substances Data: 73183-24-1(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 105-07-7 4-cyanobenzaldehyde 

Downstream Products

• 60694-99-7 1-(4-cyanophenyl)-2-phenylethan-1-one 
• 3032-92-6 4-cyanophenylacetylene 
• 1424280-47-6 C₂₇H₄₁NO₄Si 
• 121986-03-6 α-(4-cyanophenyl)-α-hydroxyacetonitrile 
• 73183-27-4 4-(2,2-Dimethyl-1,4-dioxopentyl)benzonitril 
• 104876-67-7 (4-Cyanphenyl)-2,4,6-cycloheptatrien-1-ylketon 
• 93554-86-0 4-(Amino-cyano-methyl)-benzonitrile; hydrochloride 
• 104876-63-3 (4-Cyanphenyl)-2,4,6-cycloheptatrien-1-yl(trimethylsiloxy)acetonitril 
• 73183-22-9 4-(1-Cyano-2,2-dimethyl-4-oxo-1-trimethylsilanyloxy-pentyl)-benzonitrile 
• 73183-28-5 4-(3-Oxocyclohexylcarbonyl)benzonitril 

Relevant articles and documents

A 3D In(III) coordination polymer derived from rigid dicarboxylate ligand: Synthesis, crystal structure and catalytic property

A new indium coordination polymer, In(OH)(H2O)(1,4-bdc) (1,4-H2bdc = 1, 4-benzendicarboxylic acid), has been prepared under solvothermal conditions using a mixture of rigid organic linker and inorganic heteropolyacid (12-phosphotungs

Crystal transformation in Mn(ii) metal-organic frameworks based on a one-dimensional chain precursor

The solvothermal reaction of Mn(ii) salts and 5-((4′-(tetrazol-5′′-yl)benzyl)oxy)isophthalic acid (H3L) affords an Mn(ii) based coordination polymer Mn(H2L)2(H2O)2(1), which possesses a one-dimensiona

Application of an Electrochemical Microflow Reactor for Cyanosilylation: Machine Learning-Assisted Exploration of Suitable Reaction Conditions for Semi-Large-Scale Synthesis

Cyanosilylation of carbonyl compounds provides protected cyanohydrins, which can be converted into many kinds of compounds such as amino alcohols, amides, esters, and carboxylic acids. In particular, the use of trimethylsilyl cyanide as the sole carbon source can avoid the need for more toxic inorganic cyanides. In this paper, we describe an electrochemically initiated cyanosilylation of carbonyl compounds and its application to a microflow reactor. Furthermore, to identify suitable reaction conditions, which reflect considerations beyond simply a high yield, we demonstrate machine learning-assisted optimization. Machine learning can be used to adjust the current and flow rate at the same time and identify the conditions needed to achieve the best productivity.