7327-78-8Relevant articles and documents
Synthesis and characterization of hydrazone and azine derivatives of bis(cyclopentadienyI) titanium(IV)
Kaushik, Narender Kumar,Khera, Brij,Sharma, Anand Kumar
, p. 793 - 794 (2021/11/22)
Pentacoordinated hydrazone and azine derivatives of bis(cyclopentadienyl)titanium(IV) of the type {equation presented}, have been prepared. The products were characterized by chemical analyses, elec- trical conductance, IR, 1H NMR, and electronic spectral studies. Some hydrazone complexes and a few azine com- plexes of titanium have been studied.' ' However, no systematic study on their organometallic derivatives is available. In view of the versatile chelating ability, widespread applications and lack of data involving organometallic derivatives of titanium, it has been considered of interest to study the reactions of Cp2TiCl2 with the title ligands.
New library of pyrazole–imidazo[1,2-α]pyridine molecular conjugates: Synthesis, antibacterial activity and molecular docking studies
Ebenezer, Oluwakemi,Awolade, Paul,Koorbanally, Neil,Singh, Parvesh
, p. 162 - 173 (2019/11/03)
A library of novel pyrazole–imidazo[1,2-α]pyridine scaffolds was designed and synthesized through a one-pot three-component tandem reaction. The structures of synthesized conjugates were confirmed by spectroscopic techniques (NMR, IR and HRMS). In vitro antibacterial evaluation of the twelve synthesized molecules (7a, 8a–k) against methicillin-resistant Staphylococcus aureus and normal strains of Escherichia coli, Salmonella typhimurium, Klebsiella pneumonia and Pseudomonas aeruginosa established 8b, 8d, 8e, 8h and 8i as potent antibacterial agents with superior minimum bactericidal concentration, compared with standard drug ciprofloxacin. Molecular docking studies of all active compounds into the binding site of glucosamine-6-phosphate synthase were further performed in order to have a comprehensive understanding of putative binding modes within the active sites of the receptor.
AlCl3·6H2O-catalyzed Schiff-base reaction between aryl ketones and aromatic acylhydrazines/hydrazines in water
Zhao, Zhi Xiang,Li, Ting,Cheng, Li Ping,Li, Meng,Zhong, Zhi Jian,Pang, Wan
, p. 1833 - 1839 (2019/11/05)
Abstract: Schiff-bases have important applications in the field of analysis, biomedicine, as well as material sciences. Hydrazones and acylhydrazones are two representative types of Schiff-bases. In this study, a green synthesis of aromatic hydrazones and