73290-22-9 Usage
Description
2-Bromo-5-iodopyridine is a white crystalline chemical compound characterized by the presence of both bromine and iodine atoms in its molecular structure. It is a derivative of pyridine, a heterocyclic aromatic compound, and is known for its unique chemical properties that make it a versatile building block in the synthesis of various organic compounds.
Uses
Used in Fluorescent Compounds Development:
2-Bromo-5-iodopyridine is used as a key building block for the development of fluorescent compounds, such as manisyl-substituted terpyridine, bipyridine, and phenanthroline. These compounds have a wide range of applications in the fields of bioimaging, sensing, and molecular probes due to their unique optical properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-Bromo-5-iodopyridine is used as a valuable reagent for investigating the structure/activity relationships of non-nucleoside adenosine kinase inhibitors. These inhibitors are important targets for the development of drugs to treat various diseases, including cancer and neurological disorders. By understanding the relationship between the structure of these inhibitors and their biological activity, researchers can design more effective and selective drugs.
Used in Chemical Synthesis:
2-Bromo-5-iodopyridine is also used as an intermediate in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique chemical properties, including the presence of both bromine and iodine atoms, make it a versatile and valuable building block in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 73290-22-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,2,9 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 73290-22:
(7*7)+(6*3)+(5*2)+(4*9)+(3*0)+(2*2)+(1*2)=119
119 % 10 = 9
So 73290-22-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H3BrIN/c6-5-2-1-4(7)3-8-5/h1-3H
73290-22-9Relevant articles and documents
Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships
Snegaroff, Katia,Nguyen, Tan Tai,Marquise, Nada,Halauko, Yury S.,Harford, Philip J.,Roisnel, Thierry,Matulis, Vadim E.,Ivashkevich, Oleg A.,Chevallier, Floris,Wheatley, Andrew E. H.,Gros, Philippe C.,Mongin, Florence
experimental part, p. 13284 - 13297 (2012/02/03)
A series of chloro- and bromopyridines have been deprotometalated by using a range of 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal combinations. Whereas lithium-zinc and lithium-cadmium bases afforded different mono- and diiodides after subsequent interception with iodine, complete regioselectivities were observed with the corresponding lithium-copper combination, as demonstrated by subsequent trapping with benzoyl chlorides. The obtained selectivities have been discussed in light of the CH acidities of the substrates, determined both in the gas phase and as a solution in THF by using the DFT B3LYP method.
