73323-65-6 Usage
Description
BOC-D-PRO-OME, also known as N-Boc-D-proline methyl ester, is a significant compound utilized as a raw material and intermediate in various industries, including organic synthesis, pharmaceuticals, agrochemicals, and dyestuff fields. Its unique chemical structure and properties make it a versatile component in the development of new products and applications.
Uses
Used in Organic Synthesis:
BOC-D-PRO-OME is used as a key intermediate for the synthesis of various organic compounds. Its presence in the reaction mixture allows for the formation of complex molecular structures, which are essential in the development of new materials and chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BOC-D-PRO-OME is used as a building block for the development of new drugs and therapeutic agents. Its unique properties enable the creation of novel drug candidates with potential applications in treating various diseases and medical conditions.
Used in Agrochemicals:
BOC-D-PRO-OME is employed as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products helps improve their effectiveness in controlling pests and weeds, ultimately contributing to increased crop yields and food security.
Used in Dyestuff Industry:
In the dyestuff industry, BOC-D-PRO-OME is used as a crucial component in the production of various dyes and pigments. Its presence in the dye formulation allows for the creation of vibrant and long-lasting colors, which are essential for various applications, including textiles, plastics, and printing inks.
Check Digit Verification of cas no
The CAS Registry Mumber 73323-65-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,3,2 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 73323-65:
(7*7)+(6*3)+(5*3)+(4*2)+(3*3)+(2*6)+(1*5)=116
116 % 10 = 6
So 73323-65-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO4/c1-11(2,3)16-10(14)12-7-5-6-8(12)9(13)15-4/h8H,5-7H2,1-4H3/t8-/m1/s1
73323-65-6Relevant articles and documents
Catalytic Asymmetric Hydrogenation of Heteroarenes and Arenes
Kuwano, Ryoichi
, p. 715 - 719 (2016/01/15)
A trans-chelating chiral bisphosphine, PhTRAP, allows the ruthenium-catalyzed hydrogenation of various azoles to proceed with high enantioselectivity. The PhTRAP-ruthenium catalyst transformed indoles, pyrroles, imidazoles, and oxazoles into the correspon
Enzyme-catalyzed enantiomeric resolution of N-Boc-proline as the key-step in an expeditious route towards RAMP
Kurokawa, Masayuki,Shindo, Takeyuki,Suzuki, Masumi,Nakajima, Nobuyoshi,Ishihara, Kohji,Sugai, Takeshi
, p. 1323 - 1333 (2007/10/03)
For the preparation of both enantiomers of N-carbamoyl-2-methoxymethylpyrrolidine, the precursors of Enders' chiral auxiliaries, SAMP and RAMP, enzyme-catalyzed kinetic resolution of racemic N-carbamoyl, N-Boc, N-Cbz proline esters and prolinols were examined. B. licheniformis protease (subtilisin) preferentially hydrolyzed the (R)-carbamoylproline ester with an enantiomeric ratio (E) of 10. To a hydrophobic N-Cbz proline ester, subtilisin showed lower selectivity (E=2.8), and in contrast, a purified protease (isozyme A) from the earthworm showed the preference of (S)-enantiomer (E=13.6). In a practical sense, C. antarctica lipase B (Chirazyme L-2) was effective for the hydrolysis of both N-Boc and N-Cbz derivatives with E >100. The e.e. of (R)-N-carbamoyl-2-methoxymethylpyrrolidine was raised to be >99.9% by recrystallization at the N-Boc-prolinol stage, which was derived from the (R)-N-Boc-proline methyl ester (98.7% e.e.) through a preparative-scale enzyme-catalyzed resolution (49% yield) of the racemic substrate.
