733776-45-9

Basic information

• Product Name: 6-(2,4-Dimethoxyphenyl)-nicotinic acid
• Synonyms: 6-(3,5-Dimethoxyphenyl)-nicotinic acid
• CAS NO: 733776-45-9
• Molecular Formula: C₁₄H₁₃NO₄
• Molecular Weight: 259.26
• Mol File: 733776-45-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 420.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.243±0.06 g/cm3(Predicted)
• PKA: 2.11±0.10(Predicted)
• CAS DataBase Reference: 6-(2,4-Dimethoxyphenyl)-nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2,4-Dimethoxyphenyl)-nicotinic acid(733776-45-9)
• EPA Substance Registry System: 6-(2,4-Dimethoxyphenyl)-nicotinic acid(733776-45-9)

Safety Data

• Hazardous Substances Data: 733776-45-9(Hazardous Substances Data)

Upstream product

• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 133730-34-4 2,4-dimethoxyphenylboronic acid 

Downstream Products

• 1074764-44-5 6-(2,4-dimethoxyphenyl)-N-[(2R)-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-yl]nicotinamide 

Relevant articles and documents

Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework

The use of a catalyst system based on Pd2dba3· CHCl3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha- adamantane allows for Suzuki coupling aryl halides with an array of boronic acids on a solid-phase platform. The reactions can be carried out at room temperature with low palladium loadings in high yields.