73383-95-6Relevant articles and documents
Selective butyryl cholinesterase inhibitor or pharmaceutically acceptable salt thereof as well as preparation method and application thereof
-
Paragraph 0027-0029, (2021/08/25)
The invention discloses a selective butyryl cholinesterase inhibitor or a pharmaceutically acceptable salt thereof, and a preparation method and application thereof, wherein the inhibitor has the selective butyrylcholinesterase inhibitor of the general formula (I) or the formula (II) or a pharmaceutically acceptable salt thereof. The compound or the pharmaceutically acceptable salt thereof disclosed by the invention has good in-vitro target activity and extremely high selectivity, and can be used as a leader substance for further developing an anti-'s disease through selective inhibition of butyrylcholine esterase.
Design, synthesis, antimicrobial evaluation and docking studies of urea-triazole-amide hybrids
Kumar, Anil,Kumar, Ashwani,Lal, Kashmiri,Poonia, Nisha,Rani, Poonam
, (2020/04/23)
A series of urea-1,2,3-triazole-amide hybrids was designed and synthesized via click reaction of urea derivatives containing a propargyl unit with 2-bromo-N-phenylacetamide derivatives and characterized by FTIR, NMR and HRMS data. The antimicrobial evalua
Synthesis, anticancer, and computational studies of 1, 3, 4-oxadiazole-purine derivatives
Faisal, Shahla,Kamal, Shagufta,Parveen, Bushra,Rasool, Nasir,Rasul, Azhar,Raza, Zohaib,Shahzadi, Irum,Zahid, Faisal M.,Zahoor, Ameer F.,Zia-ur-Rehman, Muhammad
, p. 2782 - 2794 (2020/04/16)
Theophylline-7-acetic acid (acefylline) (3) and its derivatives are pharmacologically active compounds and generally recognized as bronchodilators for the treatment of respiratory diseases like acute asthma for over 70 years. In this article, synthesis of