73387-74-3

Basic information

• Product Name: 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy-
• Synonyms: 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy-;3-CYANO-4-CHLORO-7-METHOXYQUINOLINE;4-chloro-7-Methoxyquinoline-3-carbonitrile
• CAS NO: 73387-74-3
• Molecular Formula: C₁₁H₇ClN₂O
• Molecular Weight: 218.63908
• Mol File: 73387-74-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 173-174 °C(Solv: chloroform (67-66-3))
• Boiling Point: 385.3°C at 760 mmHg
• Flash Point: 186.8°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 3.84E-06mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: 2-8°C
• PKA: 0.62±0.38(Predicted)
• CAS DataBase Reference: 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy-(73387-74-3)
• EPA Substance Registry System: 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy-(73387-74-3)

Safety Data

• Hazardous Substances Data: 73387-74-3(Hazardous Substances Data)

Usage

General Description

3-Quinolinecarbonitrile, 4-chloro-7-Methoxy- is a chemical compound with the molecular formula C11H8ClNO. It is a derivative of quinoline and contains a chlorine atom and a methoxy group attached to the 4th and 7th positions, respectively. 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy- is commonly used in the synthesis of various pharmaceuticals and agrochemicals. It has been studied for its potential anti-cancer and anti-inflammatory properties, making it a promising candidate for drug development. Additionally, it has been investigated for its potential as a fluorescent probe for detecting reactive oxygen species. While its exact uses and applications may vary, 3-Quinolinecarbonitrile, 4-chloro-7-Methoxy- is a versatile compound with a range of potential industrial and scientific uses.

InChI:InChI=1/C11H7ClN2O/c1-15-8-2-3-9-10(4-8)14-6-7(5-13)11(9)12/h2-4,6H,1H3

Upstream product

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Relevant articles and documents

Identification of Broad-Spectrum Dengue/Zika Virus Replication Inhibitors by Functionalization of Quinoline and 2,6-Diaminopurine Scaffolds

Social and demographic changes across the world over the past 50 years have resulted in significant outbreaks of arboviruses such as dengue virus (DENV) and Zika virus (ZIKV). Despite the increased threat of infection, no approved drugs or fully protectiv

USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS

This invention provides a method of treating or inhibiting colonic polyps which comprises providing a compound of formula (1); wherein R1, R2, R3, R4, X, Y, and n are defined hereinbefore, or a pharmaceutically acceptable salt thereof.

SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS

This invention provides compounds of formula (1) wherein R1, G1, G2, R4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof, which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.