7343-34-2Relevant articles and documents
Substituent effects on the electron transfer-initiated photochemical transformation of 1,2,4-triazole-substituted α-dehydroarylalaninamides into 2(1H)-quinolinone derivatives
Yazawa, Yuichi,Suzuki, Minoru,Igarashi, Tetsutaro,Sakurai, Tadamitsu
experimental part, p. 199 - 206 (2010/05/18)
An investigation was undertaken to elucidate substituent effects on the photoreactivity of 1,2,4-triazole-substituted α-dehydroarylalaninamides [(Z)-1] as well as on the selectivity of 2(1H)-quinolinone derivatives (2) from a synthetic point of view. It was found that photoinduced electron transfer-initiated cyclization of (Z)-1 bearing a meta-substituted phenyl or a 4-substituted naphthalen-1-yl group in methanol proceeds with a moderate to good efficiency affording the corresponding product 2 in a selectivity ranging from 33 to 100%.