73499-12-4

Basic information

• Product Name: cortisol-21-3-maleimidobenzoate
• Synonyms: cortisol-21-3-maleimidobenzoate
• CAS NO: 73499-12-4
• Molecular Formula: C32H35NO8
• Molecular Weight: 561.6222
• Mol File: 73499-12-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 769.8°C at 760 mmHg
• Flash Point: 419.4°C
• Appearance: /
• Density: 1.4g/cm³
• Vapor Pressure: 6.25E-25mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Refrigerator
• Solubility: Dichloromethane (Slightly), DMSO (Slightly)
• CAS DataBase Reference: cortisol-21-3-maleimidobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: cortisol-21-3-maleimidobenzoate(73499-12-4)
• EPA Substance Registry System: cortisol-21-3-maleimidobenzoate(73499-12-4)

Safety Data

• Hazardous Substances Data: 73499-12-4(Hazardous Substances Data)

Usage

Description

Cortisol-21-3-maleimidobenzoate is a derivative of cortisol, which is a glucocorticoid hormone produced by the zona fasciculata of the adrenal gland. It is a topical corticosteroid that is released in response to stress and low levels of blood glucocorticoids. Its primary functions include increasing blood sugar through gluconeogenesis, suppressing the immune system, and aiding in the metabolism of fat, protein, and carbohydrates.

Uses

Used in Pharmaceutical Industry:
Cortisol-21-3-maleimidobenzoate is used as a topical corticosteroid for its anti-inflammatory and immunosuppressive properties. It helps in reducing inflammation, itching, and redness associated with various skin conditions such as eczema, dermatitis, and psoriasis.
Used in Medical Applications:
Cortisol-21-3-maleimidobenzoate is used as a glucocorticoid hormone for its role in increasing blood sugar through gluconeogenesis, which is essential during stress or low blood glucocorticoid levels. It also aids in the metabolism of fat, protein, and carbohydrates, making it a valuable compound in managing various metabolic disorders.
Used in Research and Development:
Cortisol-21-3-maleimidobenzoate is used as a research compound for studying the effects of glucocorticoids on the immune system, inflammation, and metabolism. It can be employed in the development of new drugs and therapies targeting these processes.

InChI:InChI=1/C32H35NO8/c1-30-12-10-21(34)15-19(30)6-7-22-23-11-13-32(40,31(23,2)16-24(35)28(22)30)25(36)17-41-29(39)18-4-3-5-20(14-18)33-26(37)8-9-27(33)38/h3-5,8-9,14-15,22-24,28,35,40H,6-7,10-13,16-17H2,1-2H3/t22-,23-,24-,28+,30-,31-,32-/m0/s1