7352-64-9

Basic information

• Product Name: Glycine, (4-nitrophenyl)methyl ester
• CAS NO: 7352-64-9
• Molecular Formula: C9H10N2O4
• Molecular Weight: 210.189
• Mol File: 7352-64-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Glycine, (4-nitrophenyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, (4-nitrophenyl)methyl ester(7352-64-9)
• EPA Substance Registry System: Glycine, (4-nitrophenyl)methyl ester(7352-64-9)

Safety Data

• Hazardous Substances Data: 7352-64-9(Hazardous Substances Data)

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 100-14-1 4-nitrobenzyl chloride 
• 7352-63-8 p-toluenesulfonate de glycinate de p-nitrobenzyle 
• 619-73-8 4-nitrobenzyl chloride 
• 56-40-6 glycine 
• 5680-81-9 N-benzyloxycarbonyl-glycine p-nitrobenzyl ester 

Downstream Products

• 26054-98-8 N-(N-benzyloxycarbonyl-L-seryl)-glycine-(4-nitro-benzyl ester) 
• 100406-09-5 Benzyloxycarbonyl-DL-alanyl-glycin-p-nitro-benzylester 
• 102192-11-0 oxo-2 (phenyl-2 vinyl)-4 phtalimido-3 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-S,R)(E) 
• 79092-37-8 [2-[1,3]Dithian-2-yl-eth-(Z)-ylideneamino]-acetic acid 4-nitro-benzyl ester 
• 51782-11-7 Z-Cys(-CH2-Ph)-Gly-ONB 
• 2747-97-9 N--glycin-<4-nitro-benzylester> 
• 23556-78-7 (+)-N-Cbz-L-alanyl-PNB-glycinate 
• 17079-50-4 -glycin-p-nitrobenzylester 
• 17079-53-7 (N-Benzoyl-β-benzyl-α-DL-aspartyl)-glycin-p-nitrobenzylester 
• 17079-49-1 -glycin-p-nitrobenzylester 
• 17079-55-9 (N-Benzoyl-α-ethyl-β-DL-aspartyl)-glycin-p-nitrobenzylester 
• 4009-61-4 (2-Cyclohexyloxycarbonylamino-acetylamino)-acetic acid 4-nitro-benzyl ester 
• 14349-35-0 Benzyloxycarbonyl-L-glutaminyl-glycin-(4-nitro-benzylester) 
• 63349-18-8 C₁₆H₂₅N₂O₈P 

Relevant articles and documents

Vibrational spectra of N-acetylglycine oligomers. Part 2. - Raman scattering study of selectively C-deuteriated oligomers with polyglycine I- and II-type structures

Selectively C-deuteriated N-acetylglycine trimer and tetramer acid types have been synthesized, and their two crystalline modifications, solid-A and solid-B [which correspond in structure to polyglycine (PG) II and I, respectively] have been prepared. Raman scattering spectra have been measured for a series of these glycine oligomers, and the CH2- and CD2-characteristic modes have been investigated in detail. Assignment of the CH2-characteristic bands to each CH2 group in the oligomers has been carried out successfully. In particular, the results obtained from the CD2 stretch region show that N- and C-terminal glycine residues for the PGI- and PGII-type trimers and tetramers are all in very similar environments and that the glycine residues which are sandwiched between the two terminal residues are also in a similar environment for both the trimers and the tetramers.

Cleavage of Chiral 4-Phenyl-2-Oxazolidinones with TMSI: Application to the Synthesis of Carbacephems

A new technique for cleaving chiral N-substituted 4-phenyl-2-oxazolidinones is described.Thus reaction of a 7-carbacephem with TMSI and HMDS in acetonitrile, followed by DABCO, then aqueous hydrochloric acid gives the carbacephem nucleus, carbon dioxide, and acetophenone.This method allows a more versatile use of 4-phenyl-2-oxazolidinone as a chiral auxiliary and N-protective group in the synthesis of carbacephems. Key Words: trimethylsilyl iodide; chiral auxiliary; 4-phenyl-2-oxazolidinones; carbacephems; beta-lactams