73541-93-2 Usage
Description
(pyrrolidin-1-ylmethylidene)propanedinitrile, with the molecular formula C9H11N3, is a nitrile derivative featuring a five-membered ring and two nitrile functional groups. This chemical compound holds potential in the realms of organic synthesis and medicinal chemistry, serving as a versatile building block for the creation of novel compounds with pharmacological and biological activities. Its distinctive structure and properties render it an invaluable asset for chemists and researchers, enabling them to explore new chemical reactions and applications in drug discovery and development.
Uses
Used in Organic Synthesis:
(pyrrolidin-1-ylmethylidene)propanedinitrile is utilized as a key intermediate in organic synthesis, particularly for the development of new compounds with potential applications across various industries. Its unique structure allows for a wide range of chemical reactions, making it a valuable asset in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (pyrrolidin-1-ylmethylidene)propanedinitrile serves as a promising building block for the design and synthesis of novel pharmaceuticals. Its incorporation into drug candidates can potentially enhance their pharmacological properties, such as potency, selectivity, and bioavailability, leading to the development of more effective treatments for various diseases and conditions.
Used in Drug Discovery and Development:
(pyrrolidin-1-ylmethylidene)propanedinitrile is employed as a valuable tool in drug discovery and development, where its unique structure and properties can be harnessed to identify and optimize new lead compounds. Its potential to form a diverse array of chemical reactions makes it an attractive candidate for the exploration of novel drug targets and the advancement of therapeutic strategies.
Used in Chemical Research:
In the context of chemical research, (pyrrolidin-1-ylmethylidene)propanedinitrile is used as a model compound to study and understand various chemical reactions and mechanisms. Its unique structural features provide researchers with the opportunity to investigate new reaction pathways and develop innovative synthetic methodologies, ultimately contributing to the broader understanding of chemical processes and the advancement of scientific knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 73541-93-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,4 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 73541-93:
(7*7)+(6*3)+(5*5)+(4*4)+(3*1)+(2*9)+(1*3)=132
132 % 10 = 2
So 73541-93-2 is a valid CAS Registry Number.
73541-93-2Relevant articles and documents
DIRECT LITHIATION OF FUNCTIONALLY SUBSTITUTED ACRYLIC ACID DERIVATIVES; LITHIATION OF β-(2-FURANYL)- AND β-(2-THIENYL)-ACRYLIC ACIDS
Schmidt, R. R.,Hirsenkorn, R.
, p. 2043 - 2054 (1983)
Direct C-lithiation of β-functionally-substituted acrylates yields versatile building units for syntheses of butenolides, tetronates, cyclopentenones and derivatives, which are portions of many natural products.A wide variety of α- and β-substituents are compatible with this lithiation: alkyl-, aryl- and electron donating substituents in α-position or for instance an electron withdrawing ester group in β-position.Lithiation of aminomethylene malonitrile derivative 17 led to a new azafulvene 18. β-(2-Furanyl)- and β-(2-thienyl)-acrylates (23-30) were directly C-lithiated in α-, β-, or 5-position and α- or 5-position, respectively.Reactions with different electrophiles were carried out.The presence of the unprotected electrophilic carboxylic group allows for interesting ring closure reactions, for instance with carbonyl compounds to butenolides 42 and 43.The three vinylic positions (α, β and C-5) are accessible to a highly site-selective successive lithiation and reaction with electrophiles, as demonstrated for the transformation of 25 to 45 via 42 and 44.
Muscle relaxants. 3rd communication: Development of acrylic acid derivatives of potential muscle relaxing activity
Kreutzberger,Kreutzberger
, p. 232 - 234 (2007/10/02)
With reference to the occurrence of C=C partial structures and alkyl carboxylate groupings in muscle relaxants, the synthesis of acrylic acid derivatives by the aminomethinylation procedure has been followed up. From the reaction of s-triazine (1) with methyl acetoacetate (2a) and piperidine (5a), methyl 2-acetyl-3-piperidino acrylate (6a) arises. Analogously, 3-pyrrolidinoacrylophenone (6b) and 3-morpholinoacrylophenone (6c) are formed. In the same manner, the 3-component reaction comprising the interaction of 1 with malononitrile (7) and a secondary amine (5) gives rise to the formation of the aminomethylenemalononitrile structure 8.
