73590-93-9

Basic information

• Product Name: 3,5-DIMETHYL 2-CHLORMETHYL PYRIDINE.HCL
• Synonyms: 3,5-DIMETHYL 2-CHLORMETHYL PYRIDINE.HCL;3,5-diMethyl-2-chloroMethylpyridine.HCl;2-(chloroMethyl)-3,5-diMethyl Pyridine hydrochloride;Pyridine,2-(chloroMethyl)-3,5-diMethyl-, hydrochloride (1:1);3,5-dimethyl-2-chloromethylpyridine HYDROCHLORIDE;2-(CHLOROMETHYL)-3,5-DIMETHYLPYRIDINE HCL;Esomeprazole Impurity 21 HCl
• CAS NO: 73590-93-9
• Molecular Formula: C8H10ClN.HCl
• Molecular Weight: 192.08
• Product Categories: Aromatics;Heterocycles;Miscellaneous Reagents
• Mol File: 73590-93-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: 3,5-DIMETHYL 2-CHLORMETHYL PYRIDINE.HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHYL 2-CHLORMETHYL PYRIDINE.HCL(73590-93-9)
• EPA Substance Registry System: 3,5-DIMETHYL 2-CHLORMETHYL PYRIDINE.HCL(73590-93-9)

Safety Data

• Hazardous Substances Data: 73590-93-9(Hazardous Substances Data)

Usage

Chemical Properties

Beige Color

Uses

Intermediate in the preparation of Omeprazole metabolites

Upstream product

• 202932-05-6 2-hydroxymethyl-3,5-dimethylpyridine 
• 70580-28-8 C₈H₁₁NO*ClH 
• 206990-64-9 acetic acid 3,5-dimethylpyridin-2-ylmethyl ester 
• 74409-42-0 2,3,5-trimethylpyridine 1-oxide 
• 695-98-7 2,3,5-trimethyl-pyridine 

Downstream Products

• 848695-25-0 BIIB₀₂₁ 

Relevant articles and documents

Synthesis and characterization of one impurity in esomeprazole, an antiulcerative drug

During drug synthesis, control of impurities is very important to get high-qualified drugs. A number of studies have devoted to synthesize the impurities and study the structures to support the method of purification. In this paper, we first synthesize one impurity in esomeprazole, rel-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole, with readily available raw materials, simple operation procedures and relatively mild reaction. Besides, we characterized its structure by MS, IR, 1H-NMR and HPLC analyses. The purity of target compound is as high as 99.58%, which can be used as the reference substance of the impurities of esomeprazole.

Synthesis and characterization of metabolites and potential impurities of the antiulcerative drug tenatoprazole

Tenatoprazole (Ulsacare) is a recently developed antiulcerative drug used for the treatment of both erosive and nonerosive gastroesophageal reflux disease. During the bulk synthesis of tenatoprazole, we have observed four impurities (tenatoprazole N-oxide, tenatoprazole sulfone N-oxide, N-methyl tenatoprazole, and desmethoxy tenatoprazole) and two metabolites (tenatoprazole sulfide and tenatoprazole sulfone). The present work describes the synthesis and characterization of these impurities. Copyright Taylor & Francis Group, LLC.