7364-23-0

Basic information

• Product Name: p-Chloro-α-phenylbenzyl(methyl) ether
• Synonyms: p-Chloro-α-phenylbenzyl(methyl) ether
• CAS NO: 7364-23-0
• Molecular Formula: C₁₄H₁₃ClO
• Molecular Weight: 232.70542
• Mol File: 7364-23-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 305.6°C at 760 mmHg
• Flash Point: 140.3°C
• Appearance: /
• Density: 1.138g/cm³
• Vapor Pressure: 0.00147mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: p-Chloro-α-phenylbenzyl(methyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: p-Chloro-α-phenylbenzyl(methyl) ether(7364-23-0)
• EPA Substance Registry System: p-Chloro-α-phenylbenzyl(methyl) ether(7364-23-0)

Safety Data

• Hazardous Substances Data: 7364-23-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H13ClO/c1-16-14(11-5-3-2-4-6-11)12-7-9-13(15)10-8-12/h2-10,14H,1H3

Upstream product

• 831-81-2 4-chlorophenyl(phenyl)methane 
• 591-50-4 iodobenzene 
• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 1195-44-4 4-chlorobenzyl methyl ether 
• 16002-63-4 phenylmagnesium iodide 
• 538-86-3 benzyl methyl ether 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 119-56-2 (4-chlorophenyl)phenylmethanol 
• 1140-33-6 1-chloro-4-(diazo(phenyl)methyl)benzene 
• 67-56-1 methanol 
• 134-83-8 1-chloro-4-(chloro(phenyl)methyl)benzene 
• 115228-66-5 triphenyl(4-chlorophenyl)methane 
• 14845-78-4 (4-chlorophenyl)phenylethylene 
• 124-41-4 sodium methylate 

Relevant articles and documents

Visible Light-Catalyzed Benzylic C-H Bond Chlorination by a Combination of Organic Dye (Acr+-Mes) and N-Chlorosuccinimide

By combining "N-chlorosuccinimide (NCS)"as the safe chlorine source with "Acr+-Mes"as the photocatalyst, we successfully achieved benzylic C-H bond chlorination under visible light irradiation. Furthermore, benzylic chlorides could be converted to benzylic ethers smoothly in a one-pot manner by adding sodium methoxide. This mild and scalable chlorination method worked effectively for diverse toluene derivatives, especially for electron-deficient substrates. Careful mechanistic studies supported that NCS provided a hydrogen abstractor "N-centered succinimidyl radical,"which was responsible for the cleavage of the benzylic C-H bond, relying on the reducing ability of Acr?-Mes.

Dialkyl Ether Formation by Nickel-Catalyzed Cross-Coupling of Acetals and Aryl Iodides

A new substrate class for nickel-catalyzed C(sp3) cross-coupling reactions is reported. α-Oxy radicals generated from benzylic acetals, TMSCl, and a mild reductant can participate in chemoselective cross-coupling with aryl iodides using a 2,6-bis(N-pyrazolyl)pyridine (bpp)/Ni catalyst. The mild, base-free conditions are tolerant of a variety of functional groups on both partners, thus representing an attractive C-C bond-forming approach to dialkyl ether synthesis. Characterization of a [(bpp)NiCl] complex relevant to the proposed catalytic cycle is also described.

Simple and direct sp3 C-H bond arylation of tetrahydroisoquinolines and isochromans via 2,3-dichloro-5,6-dicyano-1,4- benzoquinone oxidation under mild conditions

The 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-mediated sp3 C-H bond arylation of tetrahydroisoquinolines and isochromans is described. The corresponding products were facilely synthesized via a simple nucleophilic addition reaction betwee