73661-06-0

Basic information

• Product Name: 1-Naphthalenol, 4-(phenylmethoxy)-
• CAS NO: 73661-06-0
• Molecular Formula: C17H14O2
• Molecular Weight: 250.297
• Mol File: 73661-06-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-Naphthalenol, 4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenol, 4-(phenylmethoxy)-(73661-06-0)
• EPA Substance Registry System: 1-Naphthalenol, 4-(phenylmethoxy)-(73661-06-0)

Safety Data

• Hazardous Substances Data: 73661-06-0(Hazardous Substances Data)

Upstream product

• 571-60-8 1,4-Dihydroxynaphthalene 
• 70662-30-5 1-acetoxy-4-hydroxynaphthalene 
• 5697-00-7 1,4-diacetoxynaphthalene 
• 352200-67-0 acetic acid 4-benzyloxy-naphthalen-1-yl ester 
• 100-51-6 benzyl alcohol 
• 620-05-3 iodomethylbenzene 
• 100-44-7 benzyl chloride 

Downstream Products

• 133024-36-9 (naphthyl)hydroxy-naftopidil 
• 133024-37-0 (+/-)-1-benzyloxy-4-(oxiranylmethoxy)naphthalene 
• 352200-69-2 (R)-(-)-1-benzyloxy-4-(oxiranylmethoxy)naphthalene 
• 352200-70-5 (S)-(+)-1-benzyloxy-4-(oxiranylmethoxy)naphthalene 

Relevant articles and documents

One step hair coloring compositions using salts

A hair coloring composition comprising the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an amino phenol, a naphthol, a polyhydric phenol, a catechol and mixtures thereof; wherein the composition comprising one or more oxidative hair coloring agents further comprises al least one water soluble carbonate releasing salts; and optionally a water soluble ammonium salt, is described.

Synthesis of enantiomeric 4-hydroxypropranolols from 1,4-dihydroxynaphthalene

Both (R)- and (S)-enantiomers of 4-hydroxypropranolol were effectively prepared from 1,4-dihydroxynaphthalene in eight steps. The overall yields were around 30%.

Synthesis of potential Naftopidil metabolites

The synthesis of four proposed metabolites 1-4 of Naftopidil, a selective α1-antagonist, is reported. These compounds comprise hydroxylated and demethylated derivatives and a cleavage product of Naftopidil.