73682-18-5Relevant articles and documents
Azlocillin. Ein neues Penicillin aus der Acylureidoreihe. Synthese und chemische Eigenschaften
Koenig, Hans-Bodo,Metzer, Karl-Georg,Offe, Hans-Albert,Schroeck, Wilfried
, p. 59 - 63 (2007/10/02)
Azlocillin, 6--penicillanic acid is a new semi synthetic acylureido-penicillin presenting a broad antibacterial spectrum, especially against Pseudomonas.Synthesis from ampicillin and 6-aminopenicillanic acid as well as physicochemical properties of free acid and sodium salt are described.Azlocillin is cleaved by penicillinase to penicilloate which is further degraded by acid to peniollate.Keywords: Azlocillin. - Acylureidopenicillin. - Antibacterial activity.