73697-60-6

Basic information

• Product Name: Oxiranepropanoic acid, ethyl ester
• Synonyms: 4,5-Epoxy-valeriansaeure-aethylester;Oxiranepropanoic acid,ethyl ester;Ethyl 4,5-epoxypentanoate;ETHYL 3-[(2S)-OXIRAN-2-YL]PROPANOATE;4,5-epoxy-valeric acid ethyl ester;Ethyl (R,S)-4,5-epoxypentanoate;Ethyl 4,5-epoxy-4-pentenoate
• CAS NO: 73697-60-6
• Molecular Formula: C7H12O3
• Molecular Weight: 144.17
• Mol File: 73697-60-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Oxiranepropanoic acid, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranepropanoic acid, ethyl ester(73697-60-6)
• EPA Substance Registry System: Oxiranepropanoic acid, ethyl ester(73697-60-6)

Safety Data

• Hazardous Substances Data: 73697-60-6(Hazardous Substances Data)

Upstream product

• 141-78-6 ethyl acetate 
• 106-89-8 epichlorohydrin 
• 1968-40-7 ethyl 4-pentenoate 
• 591-80-0 pent-4-enoic acid 
• 65706-95-8 Aethyl-5-brom-4-hydroxyvalerat 

Downstream Products

• 73697-53-7 4-hydroxytrimethylommoniopentanoate 
• 564484-66-8 1-allyl-5-hydroxy-piperidin-2-one 
• 871329-38-3 ethyl 4-hydroxy-5-(4-methoxyphenyl)pentanoate 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 108-29-2 5-methyl-dihydro-furan-2-one 
• 539-88-8 4-oxopentanoic acid ethyl ester 
• 1372559-44-8 ethyl 4-hydroxy-7-(3-methoxyphenyl)hept-6-ynoate 
• 1372559-47-1 (Z)-2-(3-(3-methoxyphenyl)allyl)-2,3-dihydrofuran 
• 1372559-45-9 ethyl (Z)-4-hydroxy-7-(3-methoxyphenyl)hept-6-enoate 
• 1372559-46-0 C₁₄H₁₆O₃ 
• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 
• 564484-67-9 1-allyl-piperidine-2,5-dione 
• 24962-83-2 (±)-5-(4-methoxybenzyl)dihydrofuran-2(3H)-one 
• 136576-78-8 Ethyl (R)-(+)-4,5-epoxypentanoate 

Relevant articles and documents

A process for manufacturing a δ - e lactone method (by machine translation)

The invention provides a method for manufacturing δ - e lactone of the new method. The method comprises: 1) type (I) acetic acid alkyl esters with epichlorohydrin undergo nucleophilic substitution reaction, of formula (III) 4, 5 - epoxy valeric acid alkyl ester; 2) step 1) of formula (III) of 4, 5 - epoxy valeric acid alkyl ester hydrogenation reaction of formula (IV) 5 - hydroxy valeric acid alkyl ester; 3) steps 2) of formula (IV) of the 5 - hydroxy valeric acid alkyl ester generate the cyclization reaction generating δ - e lactone. The method of the invention total reaction yield up to 95% or more. The method the raw material is cheap, small pollution to the environment, mild reaction conditions, low cost, high yield of products to be easily purified, is suitable for industrial production. (by machine translation)

A practical one-pot radical-ionic sequence for the preparation of epoxides: Application to the synthesis of unnatural polyhydroxylated alkaloids

An efficient one-pot sequence for the preparation of epoxides from α-iodoesters or α-iodonitriles and allylic alcohols is described. This sequence is based on the use of iodine atom transfer reaction onto allylic alcohols followed by a ring closing epoxidation reaction of the halohydrin intermediates. The feasibility of this sequence is showcased in the synthesis of the perhydroaza-azulene, an unnatural analog of castanospermine.

A synthetically useful, self-assembling MMO mimic system for catalytic alkene epoxidation with aqueous H2O2 [18]

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