73724-47-7

Basic information

• Product Name: L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl ester
• CAS NO: 73724-47-7
• Molecular Formula: C29H31NO5
• Molecular Weight: 473.569
• Mol File: 73724-47-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl ester(73724-47-7)
• EPA Substance Registry System: L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl ester(73724-47-7)

Safety Data

• Hazardous Substances Data: 73724-47-7(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 

Downstream Products

• 113266-08-3 O-t-butyl-L-seryl-glycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113266-08-3 O-t-butyl-D-seryl-glycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-72-6 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-D-serylglycyl-L-phenylalanyl-L-serine> benzyl ester 
• 113247-71-5 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,L-Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> benzyl ester 
• 113247-69-1 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-O-t-butyl-L-serylglycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113266-09-4 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-O-t-butyl-D-serylglycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-70-4 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-O-t-butyl-L-serylglycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113266-05-0 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-O-t-butyl-D-serylglycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-68-0 N-fluorenylmethoxycarbonyl-O-t-butyl-L-seryl-glycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-79-3 N-fluorenylmethoxycarbonyl-O-t-butyl-D-seryl-glycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-74-8 N-fluorenylmethoxycarbonyl-L-phenylalanine-O-t-butyl-L-serine benzyl ester 
• 113247-78-2 L-phenylalanine-O-t-butyl-L-serine benzyl ester 
• 113247-75-9 O-t-butyl serine benzyl ester 

Relevant articles and documents

Transesterification catalyzed by iron(III) β-diketonate species

A practical and clean protocol for transesterification catalyzed by a 5 mol % cheap, non-toxic and moisture stable Fe(acac)3 or other iron(III) β-diketonate species in solvent, such as heptane under azeotropic condition is developed. A remarkable rate enhancement was observed upon the addition of 5 mol % of an inorganic base, such as Na2CO3, which suggests that faster formation of a dimeric μ-alkoxy-bridged iron(III) species under alkaline conditions facilitates catalytic turnover. This system provides smooth transesterification over a wide range of structurally diverse esters and alcohols without disturbing functional groups. In addition, the use of iron β-diketonate complexes as catalysts is more environmentally friendly, safer, and economical than other transition-metal catalysts. Preliminary mechanistic studies indicate that the active catalyst is likely a dimeric μ-alkoxy-bridged iron(III) species, as determined by X-ray crystallography of [Fe(dbm)2(O-n-Bu)]2 derived from the alcoholysis of Fe(dbm)3 under alkaline conditions.