73739-64-7Relevant articles and documents
Une voie d'acces aux alcoxy-5 trimethyl-4,4,7a hexahydro-3aα,4,5,6,7,7aα (3H)-benzofurannones-2
Gosselin, Pascal,Rouessac, Francis,Zamarlik, Henri
, p. 192 - 198 (2007/10/02)
Starting from 2-methoxy (or ethoxy)-3,4-dihydro-2H-pyran, a series of four reactions allows to obtain a good yield of two 4-alcoxy-3,3-dimethyl-1-hydroxymethyl cyclohexenes which are converted to methylenecyclohexylacetic acids by different or sigmatropic reactions.These acids are cyclized at room temperature with concentrated sulfuric acid into bicyclic γ-lactones having a cis-junction.The stereospecificity of this reaction and the stability of the isomers obtained are discussed.