73771-79-6 Usage
Description
(1R,2R)-1,2,3,4-tetrahydrochrysene-1,2-diol, also known as trans-1,2,3,4-tetrahydrochrysene-1,2-diol, is a chrysene derivative that belongs to the class of polycyclic aromatic hydrocarbons (PAHs). As a diol compound, it features two hydroxyl (OH) functional groups. Chrysene, the parent compound, is typically found in coal tar and is recognized as a potential environmental pollutant. The (1R,2R)-1,2,3,4-tetrahydrochrysene-1,2-diol shares similar properties with other PAHs and may have implications for health and the environment. Its unique structure and characteristics could make it a candidate for research into biological activity and pharmaceutical applications.
Uses
Used in Environmental Research:
(1R,2R)-1,2,3,4-tetrahydrochrysene-1,2-diol is used as a research compound for studying the environmental and toxicological effects of PAHs. Its presence in coal tar and potential as an environmental pollutant make it a relevant subject for investigations into the impact of PAHs on ecosystems and human health.
Used in Pharmaceutical Research:
Due to its structural and chemical properties, (1R,2R)-1,2,3,4-tetrahydrochrysene-1,2-diol is used as a target molecule in pharmaceutical research. Its potential biological activity and the possibility of developing it into a therapeutic agent for various health conditions make it a promising candidate for drug discovery and development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 73771-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,7,7 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 73771-79:
(7*7)+(6*3)+(5*7)+(4*7)+(3*1)+(2*7)+(1*9)=156
156 % 10 = 6
So 73771-79-6 is a valid CAS Registry Number.
73771-79-6Relevant articles and documents
Bacterial dioxygenase-catalysed dihydroxylation and chemical resolution routes to enantiopure cis-dihydrodiols of chrysene
Boyd, Derek R.,Sharma, Narain D.,Agarwal, Rajiv,Resnick, Sol M.,Schocken, Mark J.,Gibson, David T.,Sayer, Jane M.,Yagi, Haruhiko,Jerina, Donald M.
, p. 1715 - 1723 (2007/10/03)
Biotransformation of the environmental pollutant chrysene 1 by resting cells of a mutant strain (B8/36) of the soil bacterium Sphingomonas yanoikuyae produces (+)-cis-3,4-dihydroxy-3,4-dihydrochrysene 4 which has been assigned (3S,4R) absolute configuration by stereochemical correlation with (-)-(3S,4R)-cis-3,4-dihydroxy-1,2,3,4-tetrahydrochrysene 6. Both cis-3,4-diol 6 and cis-1,2-dihydroxy-1,2,3,4-tetrahydrochrysene 12 are obtained in enantiopure form after chromatographic separation of the individual bis(2-methoxy-2-phenyl-2-trifluoromethylacetyl) (bis-MTPA) diastereoisomers of compound 6 and the MTPA diastereoisomers of bromohydrin 19, respectively, followed by hydrolysis. A new general synthetic route to cis-dihydrodiols, from the corresponding cis-tetrahydrodiol cyclic carbonates, is used to obtain both racemic and enantiopure forms of the bay-region diol 4, and the non-bay region diol 5. 1H NMR and CD spectra of the cis- and trans-dihydrodiols of chrysene are described.
Synthesis, Resolution and Racemization Studies of 1,2-Epoxy-1,2-dihydrochrysene
Boyd, Derek R.,Greene, Ruth M. E.
, p. 1535 - 1540 (2007/10/02)
(+)-1,2-Epoxy-1,2-dihydrochrysene, a major initial mammalian metabolite of chrysene, has been synthesised and assigned the configuration (1R,2S)- Kinetic studies on the spontaneous thermal racemization of (+)-1,2-epoxy-1,2-dihydrochrysene gave a barrier t
