73793-15-4

Basic information

• Product Name: 1,3,5-tri-O-benzoyl-2-O-(tert-butyldimethylsilyl)-α-D-ribofuranose
• Synonyms: 1,3,5-tri-O-benzoyl-2-O-(tert-butyldimethylsilyl)-α-D-ribofuranose
• CAS NO: 73793-15-4
• Molecular Weight: 576.719
• Mol File: 73793-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3,5-tri-O-benzoyl-2-O-(tert-butyldimethylsilyl)-α-D-ribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-tri-O-benzoyl-2-O-(tert-butyldimethylsilyl)-α-D-ribofuranose(73793-15-4)
• EPA Substance Registry System: 1,3,5-tri-O-benzoyl-2-O-(tert-butyldimethylsilyl)-α-D-ribofuranose(73793-15-4)

Safety Data

• Hazardous Substances Data: 73793-15-4(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 22224-41-5 1,3,5-tri-O-benzoyl-α-D-ribofuranoside 

Downstream Products

• 79816-15-2 N⁴-benzoyl-3',5'-O-dibenzoyl-2'-O-(tert-butyldimethylsilyl)cytidine 
• 79816-16-3 3',5'-di-O-benzoyl-2'-O-(tert-butyldimethylsilyl)-5-methyluridine 
• 73793-18-7 3',5'-di-O-benzoyl-2'-O-(tert-butyldimethylsilyl)uridine 
• 6554-17-2 N⁴-benzoyl-3',5'-di-O-benzoylcytidine 
• 54618-11-0 3',5'-di-O-benzoyluridine 
• 79816-17-4 2'-O-(tert-butyldimethylsilyl)-3'-O-benzoyluridine 

Relevant articles and documents

Synthesis of 2',3'-Differentiated Ribonucleosides via Glycosylation. Reactions with 2-O-Me or 2-O-TBDMS Ribofuranose Derivatives. 1. Pyrimidine Series

The synthesis of 2',3' asymmetrically substituted pyrimidine ribonucleosides in 70-95percent yields by using modified Vorbruggen conditions with "nonparticipating" 2-O-CH3 and 2-O-TBDMS ribofuranoses is described.Such compounds are useful synthons for oligoribonucleotide synthesis, including incorporation of "rare" bases.New and practically useful conditions for placement (using 1,2,4-triazole) and removal (KF/crown ether) of the tert-butyldimethylsilyl (TBDMS) protecting group are also reported.