73818-39-0

Basic information

• Product Name: Ethanethioic acid, (triphenylphosphoranylidene)-, S-phenyl ester
• CAS NO: 73818-39-0
• Molecular Formula: C26H21OPS
• Molecular Weight: 412.492
• Mol File: 73818-39-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanethioic acid, (triphenylphosphoranylidene)-, S-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanethioic acid, (triphenylphosphoranylidene)-, S-phenyl ester(73818-39-0)
• EPA Substance Registry System: Ethanethioic acid, (triphenylphosphoranylidene)-, S-phenyl ester(73818-39-0)

Safety Data

• Hazardous Substances Data: 73818-39-0(Hazardous Substances Data)

Upstream product

• 56377-57-2 α-bromo-S-phenyl thioacetate 
• 603-35-0 triphenylphosphine 
• 108-98-5 thiophenol 
• 73818-55-0 Bestmann ylide 

Downstream Products

• 166264-58-0 (E)-S-Phenyl 5-phenylpent-2-enethioate 
• 1376702-24-7 (E)-S-phenyl 4-hydroxybut-2-enethioate 
• 1376702-30-5 S-phenyl 2-(2-cyclohexyl-1,3-dioxolan-4-yl)ethanethioate 
• 1376702-29-2 S-phenyl 2-(2-cyclohexyl-1,3-dioxolan-4-yl)ethanethioate 
• 1376702-23-6 (E)-S-phenyl 4-((triisopropylsilyl)oxy)but-2-enethioate 
• 1334172-09-6 (2E)-3-(2-chlorophenyl)-1-(phenylsulfanyl)prop-2-en-1-one 
• 1588513-17-0 S-phenyl (E)-5-((tert-butyldimethylsilyl)oxy)pent-2-enethioate 
• 1588512-39-3 4-(phenylthio)tetrahydro-2H-pyran-2-one 
• 1588512-08-6 4-(phenylthio)dihydrofuran-2(3H)-one 

Relevant articles and documents

Enantioselective Synthesis of 3,4-Dihydropyran-2-ones via Phase-Transfer-Catalyzed Addition-Cyclization of Acetylacetone to Cinnamic Thioesters

Herein, we present the first example of synthesis of 3,4-dihydropyran-2-ones from cinnamic thioesters via a stereoselective phase-transfer-catalyzed domino Michael-cyclization reaction with acetylacetone. The reaction proceeded under the catalysis of Cinchona-derived quaternary ammonium phenoxide that, in combination with inorganic bases, provided 3,4-dihydropyran-2-ones in yields of up to 93% and enantioselectivities of up to 88% enantiomeric excess.

Nickel-catalyzed, ligand-free, diastereoselective synthesis of 3-methyleneindan-1-ols

Nickel-catalyzed, highly diastereoselective annulations between activated allenes and 2-acetylarylboronic acid or 2-formylarylboronic acids are reported. No ligand for nickel is required, and the reactions proceed efficiently at room temperature to give a broad range of substituted 3-methyleneindan-1-ols. Preliminary results of an enantioselective variant are also described.

Synthesis of (2RS,E)-3-Ethylidene-azetidine-2-carboxylic acid (rac. polyoximic acid)

Treatment of α-diazo β-ketoester 4 with a catalytic amount of rhodium (II) acetate followed by Wittig reaction with phosphorane 5 gave the isomeric phenylthioester derivative 6a and 6b. Reduction of 6a led to the corresponding allylic alcohol 7, which was further converted into the bromide 8. Dehalogenation of 8 with NaBH4/ DMF resulted in compound 9, which was deprotected with trifluoroacetic acid, giving racemic polyoximic acid (1).