73825-96-4 Usage
Description
1-(Ethylamino)-2-methyl-2-propanol is an organic compound with the molecular formula C6H15NO. It is a colorless liquid with a mild amine-like odor. 1-(Ethylamino)-2-methyl-2-propanol is characterized by the presence of an ethylamine group attached to the first carbon and a methyl group on the second carbon of a 2-propanol backbone. It is known for its reactivity and versatility in various chemical reactions, making it a valuable intermediate in the synthesis of different compounds.
Uses
1. Used in Pharmaceutical Industry:
1-(Ethylamino)-2-methyl-2-propanol is used as a key intermediate in the synthesis of broad-spectrum antifungal agents. Its unique structure allows for the development of compounds that can effectively target and inhibit fungal growth, making it a valuable component in the creation of potent antifungal medications.
2. Used in Chemical Synthesis:
Due to its reactive nature, 1-(Ethylamino)-2-methyl-2-propanol is also used as a general reagent in various chemical synthesis processes. It can be employed to produce a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals, contributing to its importance in the chemical industry.
3. Used in Research and Development:
In addition to its practical applications, 1-(Ethylamino)-2-methyl-2-propanol is also utilized in research and development settings. Its unique properties make it an interesting subject for studying various chemical reactions and mechanisms, further expanding the knowledge and understanding of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 73825-96-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,8,2 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 73825-96:
(7*7)+(6*3)+(5*8)+(4*2)+(3*5)+(2*9)+(1*6)=154
154 % 10 = 4
So 73825-96-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H15NO/c1-4-7-5-6(2,3)8/h7-8H,4-5H2,1-3H3
73825-96-4Relevant articles and documents
2-(2-Oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents
Bardiot, Dorothée,Thevissen, Karin,De Brucker, Katrijn,Peeters, Annelies,Cos, Paul,Taborda, Carlos P.,McNaughton, Michael,Maes, Louis,Chaltin, Patrick,Cammue, Bruno P. A.,Marchand, Arnaud
, p. 1502 - 1512 (2015/03/04)
From a fungicidal screen, we identified 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as fungicidal agents against Candida species, additionally characterized by antifungal activity against Aspergillus species. However, development of this series was hampered by low plasmatic stability. Introduction of a gem-dimethyl on the 6-position of the morpholin-2-one core led to considerable improvement in plasmatic stability while maintaining in vitro antifungal activity. Further optimization of the series resulted in the discovery of N-(biphenyl-3-ylmethyl)-2-(4-ethyl-6,6-dimethyl-2-oxomorpholin-3-yl)acetamide (87), which, in addition to fungicidal activity against Candida species, shows promising and broad antifungal in vitro activity against various fungi species, such as molds and dermatophytes. In vivo efficacy was also demonstrated in a murine model of systemic Candida albicans infection with a significant fungal load reduction in kidneys.
ANTIFUNGAL COMPOUNDS
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Page/Page column 66; 68, (2011/07/07)
The present invention relates to a series of novel compounds which have been shown to possess antifungal activity. The invention therefore relates to the new compounds, methods for their preparation, pharmaceutical compositions comprising them and to the compounds for use as a medicament, more in particular antifungal medicament.