7383-56-4Relevant articles and documents
METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE
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Paragraph 0095; 0096; 0097, (2014/02/15)
The present invention is related to a method for the synthesis of N- (phosphonomethyl)glycine or one of its derivatives selected from the group consisting of its salts, its phosphonate esters, or its phosphonate ester salts, which includes the steps of: ? a) forming, in the presence an acid catalyst, a reaction mixture comprising 2,5- diketopiperazine, formaldehyde and a compound comprising one or more P-0-P anhydride moieties, said moieties having one P atom at the oxidation state (+ III) and the other P atom at the oxidation state (+III) or (+V), to form Ν,Ν'- bisphosphonomethyl-2,5-diketopiperazine, its mono- to tetra phosphonate esters, the dehydrated forms of Ν,Ν'- bisphosphonomethyl-2,5-diketopiperazine and the phosphonate esters of its dehydrated forms; ? b) hydrolysing said N,N'-bisphosphonomethyl-2,5-diketopiperazine, its dehydrated forms or their phosphonate esters to obtain N- (phosphonomethyl)glycine or one of its derivatives selected from the group consisting of its salts, its phosphonate esters and its phosphonate ester salts.