73900-14-8

Basic information

• Product Name: 1-bromo-4-(diazomethyl)benzene
• Synonyms: 1-bromo-4-(diazomethyl)benzene
• CAS NO: 73900-14-8
• Molecular Weight: 197.034
• Mol File: 73900-14-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1-bromo-4-(diazomethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-4-(diazomethyl)benzene(73900-14-8)
• EPA Substance Registry System: 1-bromo-4-(diazomethyl)benzene(73900-14-8)

Safety Data

• Hazardous Substances Data: 73900-14-8(Hazardous Substances Data)

Upstream product

• 19350-68-6 p-bromobenzaldehyde tosylhydrazone 
• 1122-91-4 4-bromo-benzaldehyde 
• 57477-93-7 hydrazone of p-bromobenzaldehyde 

Downstream Products

• 1064075-16-6 C₁₂H₁₂BrNO₃ 
• 40155-54-2 ethyl 4-(4-bromophenyl)-2,4-dioxobutanoate 

Relevant articles and documents

Adiabatic process of higher electronically excited states: luminescence from an excited state biradical generated by irradiation of benzophenone-substituted cyclopropanes

Adiabatic photochemical reactions of cyclopropanes possessing a benzophenone moiety (trans- and cis-5), which generate a luminescent excited biradical 16??*, were studied. Various photochemical and spectroscopic techniques were used for this purpose. Excitation (350 nm, n,π* band) of 5 at 77?K affords the lowest excited state 15* that undergoes intersystem crossing to form 35*, which deactivates through phosphorescence. In contrast, 295-nm excitation (π,π* band) of 5 affords the higher electronically excited state 15**, which undergoes adiabatic C–C bond cleavage reaction to form the excited biradical 16??* that luminesces at 630?nm. The results suggest that 5 follows 2 photoreaction modes depending on the excitation wavelength, a finding that disobeys Kasha's rule.

Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines

We report herein the asymmetric coupling of flow-generated unstabilized diazo compounds and propargylated amine derivatives, using a new pyridinebis(imidazoline) ligand, a copper catalyst and base. The reaction proceeds rapidly, generating chiral allenes in 10–20 minutes with high enantioselectivity (89–98 % de/ee), moderate yields and a wide functional group tolerance.

SMALL MOLECULE LFA-1 INHIBITORS

The present invention relates to novel compounds which are capable of inhibiting the interaction of LFA-1 with its counter ligands.