73941-29-4

Basic information

• Product Name: O-(2-Phenoxyethyl)hydroxylamine
• Synonyms: O-(2-Phenoxyethyl)hydroxylamine
• CAS NO: 73941-29-4
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.1784
• Mol File: 73941-29-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 286.7°Cat760mmHg
• Flash Point: 144.4°C
• Appearance: /
• Density: 1.094g/cm³
• Vapor Pressure: 0.000258mmHg at 25°C
• CAS DataBase Reference: O-(2-Phenoxyethyl)hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: O-(2-Phenoxyethyl)hydroxylamine(73941-29-4)
• EPA Substance Registry System: O-(2-Phenoxyethyl)hydroxylamine(73941-29-4)

Safety Data

• Hazardous Substances Data: 73941-29-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H11NO2.ClH/c9-11-7-6-10-8-4-2-1-3-5-8;/h1-5H,6-7,9H2;1H

Upstream product

• 589-10-6 phenoxyethyl bromide 
• 338406-38-5 N-(2-phenoxyethoxy)phthalimide 
• 622-86-6 2-chloroethoxybenzene 
• 122-99-6 2-Phenoxyethanol 

Downstream Products

• 191472-69-2 5-Isopropyl-6-methanesulfonyl-1-(2-phenoxy-ethoxy)-1H-pyrimidine-2,4-dione 
• 191472-43-2 5-Isopropyl-6-methylsulfanyl-1-(2-phenoxy-ethoxy)-1H-pyrimidine-2,4-dione 
• 191472-00-1 C₁₇H₂₄N₂O₄S₂ 
• 41776-67-4 3-[(2-phenoxy-ethoxyimino)-methyl]-rifamycin 

Relevant articles and documents

A new supported reagent for the parallel synthesis of primary and secondary O-alkyl hydroxylamines through a base-catalyzed Mitsunobu reaction

The growing field of applications of O-alkyl hydroxylamines in medicinal chemistry and chemical biology has motivated the search for a parallel synthesis. A solid-phase approach based on the alkylation by alcohols of a new supported N-hydroxyphthalimide reagent using a Mitsunobu reaction followed by methylaminolysis has been optimized. This study points out the importance of the linker and a specific base effect for the Mitsunobu reaction. A large variety of alcohols can be used to give with moderate to high yields diverse O-alkyl hydroxylamines in high purity.