73963-70-9

Basic information

• Product Name: 6-[3-(1-Phenyltetrazol-5-yl)propoxy]-3,4-dihydrocarbostyril
• CAS NO: 73963-70-9
• Molecular Weight: 349.392
• Mol File: 73963-70-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-[3-(1-Phenyltetrazol-5-yl)propoxy]-3,4-dihydrocarbostyril(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[3-(1-Phenyltetrazol-5-yl)propoxy]-3,4-dihydrocarbostyril(73963-70-9)
• EPA Substance Registry System: 6-[3-(1-Phenyltetrazol-5-yl)propoxy]-3,4-dihydrocarbostyril(73963-70-9)

Safety Data

• Hazardous Substances Data: 73963-70-9(Hazardous Substances Data)

Upstream product

• 54197-66-9 3,4-dihydro-6-hydroxy-2(1H)-quinolinone 
• 73963-34-5 5-(3-chloropropyl)-1-phenyl-1H-tetrazole 

Relevant articles and documents

Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. II. 6-[3-(1-Cyclohexyl-5-tetrazolyl)propoxy]-1,2-dihydro-2-oxoquinoline and related compounds

A series of ω-(1-substituted-5-tetrazolylalkoxy)-2-oxoquinolines was synthesized and tested for inhibitory activity towards collagen- and adenosine diphosphate (ADP)-induced aggregation of rabbit blood platelets in vitro. These compounds were prepared by the reaction of 1-substituted-5-(ω-chloroalkyl)-tetrazoles and hydroxy-2-oxoquinolines in the presence of a base. Among them, 6-[3-(1-cyclohexyl-5-tetrazolyl)propoxy]-1,2-dihydro-2-oxoquinoline (IVb) was found to have the most potent inhibitory activity. The structure-activity relationships are discussed.