7403-75-0 Usage
Description
3-Nitro-4-acetamidophenol, with the CAS number 7403-75-0, is a chemical compound that is characterized as a yellow solid. It is primarily recognized for its utility in the field of organic synthesis, where it serves as a valuable intermediate for the creation of various complex organic molecules.
Uses
Used in Organic Synthesis:
3-Nitro-4-acetamidophenol is used as a synthetic intermediate for the production of a wide range of organic compounds. Its unique chemical structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
Within the pharmaceutical industry, 3-Nitro-4-acetamidophenol is utilized as a key component in the development of new drugs. Its reactivity and structural properties make it suitable for the synthesis of various drug candidates, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Nitro-4-acetamidophenol is employed as a starting material for the synthesis of pesticides and other crop protection agents. Its use in this industry contributes to the development of more effective and environmentally friendly solutions for agricultural challenges.
Used in Dye and Pigment Industry:
3-Nitro-4-acetamidophenol is also used as a precursor in the production of dyes and pigments. Its yellow solid form can be further modified to create a variety of colors, which are then used in various applications such as textiles, plastics, and printing inks.
Used in Research and Development:
Due to its unique chemical properties, 3-Nitro-4-acetamidophenol is often utilized in research and development settings. Scientists and chemists use this compound to study various chemical reactions and to develop new methodologies for organic synthesis, potentially leading to advancements in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 7403-75-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,0 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7403-75:
(6*7)+(5*4)+(4*0)+(3*3)+(2*7)+(1*5)=90
90 % 10 = 0
So 7403-75-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2O4/c1-5(11)9-7-3-2-6(12)4-8(7)10(13)14/h2-4,12H,1H3,(H,9,11)
7403-75-0Relevant articles and documents
Acylamino-Directed Specific Sequential Difunctionalizations of Anilides via Metal-Free Relay Reactions for p-Oxygen and o-Nitrogen Incorporation
Wan, Yameng,Zhang, Zhiguo,Ma, Nana,Bi, Jingjing,Zhang, Guisheng
, p. 780 - 791 (2019/01/24)
Novel acylamino-directed relay disubstitutions realize the sequential difunctionalizations of anilides (1) under mild and metal-free conditions for the first time. This [bis(trifluoroacetoxy)iodo]benzene (PIFA) and BF3·Et2O promoted straightforward reaction produces a series of p-acetoxyl- or p-alkoxyl-o-nitro-N-arylamides (2), which are key scaffolds of various drugs, functional materials, and bioactive molecules. The flexibility with respect to the functional groups in these products affords this novel protocol excellent versatility for synthetic applications.
Regioselective Green Electrochemical Approach to the Synthesis of Nitroacetaminophen Derivatives
Salahifar, Eslam,Nematollahi, Davood,Bayat, Mehdi,Mahyari, Amir,Amiri Rudbari, Hadi
, p. 4666 - 4669 (2015/10/12)
A regioselective green synthesis of nitroacetaminophen derivatives was carried out by electrochemical oxidation of acetaminophen, N-(2-hydroxyphenyl)acetamide, and 1-(4-(4-hydroxyphenyl)piperazin-1-yl)ethanone in the presence of nitrite ion as a nucleophile. The present work has led to the development of a reagentless green and facile electrochemical method for the synthesis of some nitroacetaminophen derivatives.
Reductive cyclization with baker's yeast of 4-alkyl-2-nitro-acetanilides to 6-alkylbenzimidazoles and 1-hydroxy-2-methyl-6-alkylbenzimidazoles
Navarro-Ocana,Olguin,Luna,Jimenez-Estrada,Barzana
, p. 2754 - 2756 (2007/10/03)
Reduction of 4-substituted 2-nitroacetanilides by baker's yeast in acid media effected cyclization, resulting in the formation of n-substituted 2-methylbenzimidazoles and 6-substituted 1-hydroxy-2-methylbenzimidazole via the chemo- and regioselective reduction of the 2-nitro aromatic group to amine or hydroxylamine.
