74035-75-9Relevant articles and documents
Synthesis and biological activity of 8β-substituted hydrocodone indole and hydromorphone indole derivatives
Yu, Han,Prisinzano, Thomas,Dersch, Christina M.,Marcus, Jamila,Rothman, Richard B.,Jacobson, Arthur E.,Rice, Kenner C.
, p. 165 - 168 (2007/10/03)
The 8β-unsubstituted and substituted analogues of hydrocodone indole and hydromorphone indole were synthesized and their binding affinities to opioid receptors were determined. Introduction of an 8β-methyl group into the indolomorphinan nucleus increased