74050-20-7 Usage
Description
Hydrocortisone aceponate is a 17-a-propionate derivative of hydrocortisone-21-acetate, a glucocorticosteroid. It is a new topical hydrocortisone derivative with esterification in positions 17 and 21, and is reportedly significantly superior to hydrocortisone-21-acetate in the treatment of dermatoses of varying severity.
Uses
Used in Pharmaceutical Industry:
Hydrocortisone aceponate is used as a topical medication for the treatment of dermatoses of varying severity. It is less strongly inhibitory to the incorporation of [3H]thymidine in DNA in human skin fibroblasts compared to the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. This makes it a promising alternative for managing skin conditions with fewer side effects.
Originator
Beiersdorf (W.Germany)
Check Digit Verification of cas no
The CAS Registry Mumber 74050-20-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,0,5 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 74050-20:
(7*7)+(6*4)+(5*0)+(4*5)+(3*0)+(2*2)+(1*0)=97
97 % 10 = 7
So 74050-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C26H36O7/c1-5-22(31)33-26(21(30)14-32-15(2)27)11-9-19-18-7-6-16-12-17(28)8-10-24(16,3)23(18)20(29)13-25(19,26)4/h12,18-20,23,29H,5-11,13-14H2,1-4H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1