74054-23-2

Basic information

• Product Name: N-hexylacridin-9-amine
• Synonyms: 9-Acridinamine, N-hexyl-
• CAS NO: 74054-23-2
• Molecular Formula: C₁₉H₂₂N₂
• Molecular Weight: 278.3914
• Mol File: 74054-23-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 450.7°C at 760 mmHg
• Flash Point: 226.3°C
• Density: 1.1g/cm³
• Vapor Pressure: 2.59E-08mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: N-hexylacridin-9-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-hexylacridin-9-amine(74054-23-2)
• EPA Substance Registry System: N-hexylacridin-9-amine(74054-23-2)

Safety Data

• Hazardous Substances Data: 74054-23-2(Hazardous Substances Data)

Upstream product

• 110166-26-2 aminacrine 
• 544-10-5 1-Chlorohexane 
• 1207-69-8 9-Chloroacridine 
• 91-40-7 2-(phenylamino)benzoic acid 
• 111-26-2 hexan-1-amine 
• 2148-14-3 9-phenoxyacridine 

Relevant articles and documents

Synthesis and evaluation of N-alkyl-9-aminoacridines with antibacterial activity

A series of 9-alkylaminoacridines were synthesized and evaluated for activity against two strains of methicillin-resistant and one strain of methicillin-sensitive Staphylococcus aureus. Results are presented that show a clear structure activity relationship between the N-alkyl chain length and antibacterial activity with peak MIC99 values of 2-3 μM for alkyl chains ranging from 10 to 14 carbons in length. Although prior work has linked the function of acridine-based compounds to intercalation and topoisomerase inhibition, the present results show that 9-alkylaminoacridines likely function as amphiphilic membrane-active disruptors potentially in a similar manner as quaternary ammonium antimicrobials.