74067-18-8Relevant articles and documents
PERFLUORINATED INTERNAL α-OXIDES IN REACTION WITH SODIUM METHOXIDE
Zapevalov, A. Ya.,Filyakova, T. I.,Peschanskii, N. V.,Kodess, M. I.,Kolenko, I. P.
, p. 441 - 445 (2007/10/02)
Perfluorinated internal α-oxides interact with sodium methoxide in methanol, giving the products from "haloform" dissociation of the intermediately formed α-methoxy-perfluoro ketones.In unsymmetrical disubstituted perfluorinated internal α-oxides nucleophilic attack by the methoxide ion is directed at both carbon atoms of the epoxide ring, while the trisubstituted perfluorinated α-oxides from the products from regiospecyfic opening of the ring.The stability of the α-oxides to the action of sodium methoxide increases with increase in the size of the perfluoroalkyl substituents in the epoxide ring.
