74160-60-4

Basic information

• Product Name: 4-aminophenyl 6-phospho-alpha-mannopyranoside
• Synonyms: 4-aminophenyl 6-phospho-alpha-mannopyranoside;4-Aminophenyl-6-phosphono-alpha-D-mannopyranoside
• CAS NO: 74160-60-4
• Molecular Formula: C12H18 N O9 P
• Molecular Weight: 351.25
• Mol File: 74160-60-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 680.7°C at 760 mmHg
• Flash Point: 365.5°C
• Appearance: /
• Density: 1.698g/cm³
• Vapor Pressure: 1.85E-19mmHg at 25°C
• Refractive Index: 1.66
• PKA: 1.86±0.10(Predicted)
• CAS DataBase Reference: 4-aminophenyl 6-phospho-alpha-mannopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aminophenyl 6-phospho-alpha-mannopyranoside(74160-60-4)
• EPA Substance Registry System: 4-aminophenyl 6-phospho-alpha-mannopyranoside(74160-60-4)

Safety Data

• Hazardous Substances Data: 74160-60-4(Hazardous Substances Data)

Usage

Description

4-aminophenyl 6-phospho-alpha-mannopyranoside is a complex carbohydrate derivative that possesses unique structural and functional properties. It is characterized by the presence of an aminophenyl group and a phosphorylated mannopyranoside moiety, which contribute to its specific interactions with biological systems. This molecule has garnered significant interest due to its potential applications in various fields, particularly in the realm of drug delivery and molecular targeting.

Uses

Used in Pharmaceutical Industry:
4-aminophenyl 6-phospho-alpha-mannopyranoside is used as a targeting agent for the specific delivery of therapeutic molecules, such as small interfering RNA (siRNA), to hepatocytes. This application is particularly relevant in the treatment of liver-related diseases, as it allows for the selective and efficient delivery of siRNA to liver cells, thereby reducing off-target effects and improving the overall therapeutic outcome.
The use of 4-aminophenyl 6-phospho-alpha-mannopyranoside in targeted drug delivery systems is based on its ability to selectively bind to specific receptors or molecular targets on the surface of hepatocytes. This selective binding enables the preferential uptake of the drug-laden molecule by the target cells, leading to a more precise and effective treatment strategy.
In addition to its application in the pharmaceutical industry, 4-aminophenyl 6-phospho-alpha-mannopyranoside may also find utility in other fields, such as biotechnology and materials science, where its unique structural and functional properties can be harnessed for the development of novel biomaterials, sensors, or diagnostic tools.

InChI:InChI=1/C12H18NO9P/c13-6-1-3-7(4-2-6)21-12-11(16)10(15)9(14)8(22-12)5-20-23(17,18)19/h1-4,8-12,14-16H,5,13H2,(H2,17,18,19)/t8-,9-,10+,11+,12+/m1/s1