74174-28-0Relevant articles and documents
New synthetic routes to biologically interesting geranylated flavanones and geranylated chalcones: First total synthesis of (±)-prostratol F, xanthoangelol, and (±)-lespeol
Jung, Doo Hwan,Lee, Yong Rok,Kim, Sung Hong
experimental part, p. 635 - 647 (2010/07/02)
A new and efficient synthetic approach to biologically interesting geranylated flavanones and geranylated chalcones is described. Thus, the first total syntheses of the geranylated flavanones (±)-prostratol F (1), (±)-8-geranyl-3′,4′,7-trihydroxyflavanone (2), and (±)-6-geranyl-5,7-dihydroxy-3′,4′-dimethoxyflavanone (3) were carried out starting from 2,4-dihydroxyacetophenone (10) and 2,4,6-trihydroxyacethophenone (17) in five to six steps (Schemes 2 and 3). The geranylated chalcones xanthoangelol (4), 3-geranyl-2,3′,4,4′- tetrahydroxychalcone (5), (±)-lespeol (6), and lespeol derivatives (±)-7-9 were synthesized starting from 2,4-dihydroxyacetophenone (10) in three to four steps (Schemes 2 and 6).
Studies on the Constituentes of Lespedeza cyrtobotrya MIQ. I. The Structures of a New Chalcone and Two New Isoflav-3-ens
Miyase, Toshio,Ueno, Akira,Noro, Tadataka,Fukushima, Seigo
, p. 1172 - 1177 (2007/10/02)
The bark of Lespedeza cyrtobotrya MIQ. afforded a new chalcone, lespeol (I), together with xanthoangelol (II).The heartwood of Lespedeza cyrtobotrya MIQ. afforded two new isoflav-3-ens, haginin A (IIIa) and B (IVa), together with genistein, daidzein, dalbergioidin, 3,9-dihydroxypterocarp-6a-en and isoliquiritigenin.The structures were established on the basis of chemical and spectral data. Keywords---Lespedeza cyrtobotrya MIQ.; lespeol; xanthoangelol; haginin A; haginin B; 3,9-dihydroxypterocarp-6a-en; genistein; daidzein; dalbergioidin; isoliquiritigenin