74185-77-6

Basic information

• Product Name: Benzene, 1,1'-(1-fluoro-1,2-ethanediyl)bis-
• CAS NO: 74185-77-6
• Molecular Formula: C14H13F
• Molecular Weight: 200.256
• Mol File: 74185-77-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(1-fluoro-1,2-ethanediyl)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1-fluoro-1,2-ethanediyl)bis-(74185-77-6)
• EPA Substance Registry System: Benzene, 1,1'-(1-fluoro-1,2-ethanediyl)bis-(74185-77-6)

Safety Data

• Hazardous Substances Data: 74185-77-6(Hazardous Substances Data)

Upstream product

• 350-62-9 1,1-difluoro-1,2-diphenylethane 
• 71370-23-5 1-chloro-2-fluoro-1,2-diphenylethane 
• 1786-37-4 (1-bromo-2-fluoroethane-1,2-diyl)dibenzene 
• 109-99-9 tetrahydrofuran 
• 122-78-1 phenylacetaldehyde 
• 591-50-4 iodobenzene 
• 151588-82-8 (2-fluoro-2-iodoethyl)benzene 
• 151588-78-2 (2-bromo-2-fluoroethyl)benzene 
• 825-76-3 α-cyclopropylstyrene 
• 108-86-1 bromobenzene 
• 98-80-6 phenylboronic acid 
• 100-42-5 styrene 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 94942-89-9 2,3-diphenylpropanoic acid 

Relevant articles and documents

Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C-H bonds

Acyl fluorides are versatile acylating agents owing to their unique stability. Their synthesis, however, can present challenges and is typically accomplished through deoxyfluorination of carboxylic acids. Here, we demonstrate that acyl fluorides can be prepared directly from aldehydes via a C(sp2)-H fluorination reaction involving the inexpensive photocatalyst sodium decatungstate and electrophilic fluorinating agent N-fluorobenzenesulfonimide. This convenient fluorination strategy enables direct conversion of aliphatic and aromatic aldehydes into acylating agents.

Combinatorial Nickel-Catalyzed Monofluoroalkylation of Aryl Boronic Acids with Unactivated Fluoroalkyl Iodides

A combinatorial nickel-catalyzed cross-coupling between arylboronic acids and unactived 1-fluoro-1-iodoalkanes has been developed, which demonstrated high efficiency, mild conditions, and excellent functional-group compatibility. Readily available nitrogen and phosphine ligands were combined with a nitrogen source, which in situ generated a variety of easily tunable catalysts to promote the fluoroalkylation for broad scopes of both coupling partners. This new strategy on combinatorial catalysis offers new solutions for nickel-catalyzed cross-coupling reactions.

Silver-catalyzed Meerwein arylation: Intermolecular and intramolecular fluoroarylation of styrenes

The first example of silver-catalyzed intermolecular and intramolecular Meerwein fluoroarylation of styrenes with aryl diazonium salts has been developed. This reaction is operationally simple, scalable and proceeds under mild conditions. Furthermore, fluorinated dihydrobenzofurans and indolines were easily accessed using this method. This journal is