74185-81-2

Basic information

• Product Name: Benzene, (1-fluoro-1-methylethyl)-
• CAS NO: 74185-81-2
• Molecular Formula: C9H11F
• Molecular Weight: 138.185
• Mol File: 74185-81-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, (1-fluoro-1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (1-fluoro-1-methylethyl)-(74185-81-2)
• EPA Substance Registry System: Benzene, (1-fluoro-1-methylethyl)-(74185-81-2)

Safety Data

• Hazardous Substances Data: 74185-81-2(Hazardous Substances Data)

Upstream product

• 2241846-03-5 1,3-dioxoisoindolin-2-yl 2-methyl-2-phenylpropanoate 
• 24142-63-0 O-(methoxymethyl)-2-phenyl-2-propanol 
• 826-55-1 2-methyl-2-phenylpropionic acid 
• 98-82-8 Isopropylbenzene 
• 108-88-3 toluene 
• 100-41-4 ethylbenzene 
• 617-94-7 1-methyl-1-phenylethyl alcohol 

Relevant articles and documents

A Series of Deoxyfluorination Reagents Featuring OCF2Functional Groups

Research on perfluoroalkyl ether carboxylic acids (PFECAs) as alternatives for perfluoroalkyl substances continues with the goal of protecting the environment. However, very little is known about the utilization of decomposition products of PFECAs. We report herein a new series of deoxyfluorination reagents featuring OCF2 functional groups derived from certain PFECAs. Alkyl fluorides were generated from various alcohols in ≤97% yield by these novel reagents. The mechanistic experiment verified in situ generation of carbonic difluoride (COF2).

Predictable site-selective radical fluorination of tertiary ethers

In this communication, we disclose the first example of metal-free and site-selective radical fluorination of readily available tertiary alkyl ethers, enabled by synergistic photocatalysis and organocatalysis. This catalytic combination allows for exclusi

Tetramethylfluoroformamidinium hexafluorophosphate (TFFH) as a mild deoxofluorination reagent

The solid, air-stable peptide coupling reagent TFFH (tetramethylfluoroformamidinium hexafluorophosphate) was found to activate a variety of alcohols towards deoxofluorination. These conditions are compatible with carbonyl functional groups thus offering interesting possibilities for the application to sensitive molecules. Georg Thieme Verlag Stuttgart · New York.