7420-22-6

Basic information

• Product Name: .beta.-D-Galactopyranoside, 2-hydroxyethyl
• Synonyms: .beta.-D-Galactopyranoside, 2-hydroxyethyl
• CAS NO: 7420-22-6
• Molecular Weight: 0
• Mol File: 7420-22-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: .beta.-D-Galactopyranoside, 2-hydroxyethyl(CAS DataBase Reference)
• NIST Chemistry Reference: .beta.-D-Galactopyranoside, 2-hydroxyethyl(7420-22-6)
• EPA Substance Registry System: .beta.-D-Galactopyranoside, 2-hydroxyethyl(7420-22-6)

Safety Data

• Hazardous Substances Data: 7420-22-6(Hazardous Substances Data)

Upstream product

• 35023-69-9 1-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)-2-hydroxyethane 

Relevant articles and documents

Experimental measurement of carbohydrate-aromatic stacking in water by using a dangling-ended DNA model system

Protein-carbohydrate recognition is of fundamental importance for a large number of biological processes; carbohydrate-aromatic stacking is a widespread, but poorly understood, structural motif in this recognition. We describe, for the first time, the measurement of carbohydrate-aromatic interactions from their contribution to the stability of a dangling-ended DNA model system. We observe clear differences in the energetics of the interac-tions of several monosaccharides with a benzene moiety depending on the number of hydroxy groups, the stereochemistry, and the presence of a methyl group in the pyranose ring. A fucose-benzene pair is the most stabi-lizing of the studied series (-0.4 Kcal mol-1) and this interaction can be placed in the same range as other more studied interactions with aromatic residues of proteins, such as Phe-Phe, Phe-Met, or Phe-His. The noncovalent forces involved seem to be dispersion forces and nonconventional hydrogen bonds, whereas hydrophobic effects do not seem to drive the interaction.