7420-49-7 Usage
Description
(1E)-phenylethanal thiosemicarbazone, also known as PETT, is a versatile chemical compound belonging to the thiosemicarbazone class. It is synthesized from phenylethanal and thiosemicarbazide and is recognized for its ability to form stable complexes with various metal ions. PETT has demonstrated promising antimicrobial and antitumor activities, positioning it as a potential candidate for drug development. Furthermore, its potential use in colorimetric and fluorescent sensing of metal ions showcases its broad applicability across different scientific and industrial fields.
Uses
Used in Medicinal Chemistry:
(1E)-phenylethanal thiosemicarbazone is used as a pharmaceutical candidate for its antimicrobial and antitumor properties. It has shown potential in treating various types of cancer and infections, making it a valuable asset in drug development.
Used in Coordination Chemistry:
(1E)-phenylethanal thiosemicarbazone is used as a ligand for forming stable complexes with metal ions. This application is crucial in understanding the coordination properties of metal ions and their potential uses in various chemical reactions and processes.
Used in Analytical Chemistry:
(1E)-phenylethanal thiosemicarbazone is used as a colorimetric and fluorescent sensor for detecting and analyzing metal ions. Its sensitivity and selectivity make it a valuable tool in analytical chemistry for environmental monitoring, industrial processes, and scientific research.
Used in Drug Development:
(1E)-phenylethanal thiosemicarbazone is used as a lead compound in the development of new drugs targeting cancer and infectious diseases. Its unique properties and potential to form complexes with metal ions make it a promising candidate for creating effective therapeutic agents.
Used in Environmental Monitoring:
(1E)-phenylethanal thiosemicarbazone is used as a tool for detecting and analyzing metal ion contaminants in environmental samples. Its application in colorimetric and fluorescent sensing allows for the efficient and accurate monitoring of metal ion levels, contributing to environmental protection and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 7420-49-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,2 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7420-49:
(6*7)+(5*4)+(4*2)+(3*0)+(2*4)+(1*9)=87
87 % 10 = 7
So 7420-49-7 is a valid CAS Registry Number.
7420-49-7Relevant articles and documents
PhI-Catalyzed Intramolecular Oxidative Coupling Toward Synthesis of 2-Amino-1,3,4-Thiadizoles
Han, Yingzhi,Sun, Yadong,Abdukader, Ablimit,Liu, Bifu,Wang, Duozhi
, p. 3486 - 3491 (2018/09/27)
A highly efficient method for the synthesis of thiadiazole derivatives via intramolecular oxidative coupling of thiosemicarbazide, using the in situ generated hypervalent iodine(III) reagents is developed. The protocol can be carried out smoothly and provides a variety of thiadiazole derivatives in moderate to excellent yields. Graphical Abstract: A highly efficient method for the synthesis of thiadiazole derivatives via PhI-catalyzed intramolecular oxidative coupling of thiosemicarbazide has been developed.
