742690-47-7Relevant articles and documents
Synthesis and biological activity of 2-aminothiazoles as novel inhibitors of PGE2 production in cells
Smith, Breland,Chang, Hui-Hua,Medda, Federico,Gokhale, Vijay,Dietrich, Justin,Davis, Angela,Meuillet, Emmanuelle J.,Hulme, Christopher
experimental part, p. 3567 - 3570 (2012/07/03)
This Letter presents the synthesis and biological evaluation of a collection of 2-aminothiazoles as a novel class of compounds with the capability to reduce the production of PGE2 in HCA-7 human adenocarcinoma cells. A total of 36 analogs were